Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4052162 | 1.00 | LMNA (0.47) | LMNAMAPK1KMT2AHPGDCES2 | |
| SCHEMBL4050550 | 1.00 | LMNA (0.47) | LMNAMAPK1KMT2AHPGDCES2 | |
| SCHEMBL4053318 | 0.85 | ALDH1A1 (0.41) | LMNAKDM4EALDH1A1 | |
| SCHEMBL4051755 | 0.82 | MEN1 (0.49) | LMNAMAPK1KMT2ATSHRALDH1A1 | |
| SCHEMBL4061773 | 0.82 | MEN1 (0.49) | LMNAMAPK1KMT2ATSHRALDH1A1 | |
| SCHEMBL4057260 | 0.75 | NAAA (0.52) | LMNAMAPK1TSHRNAAANPC1 | |
| SCHEMBL4364759 | 0.75 | NAAA (0.52) | LMNAMAPK1TSHRNAAANPC1 | |
| SCHEMBL4058968 | 0.75 | NAAA (0.52) | LMNAMAPK1TSHRNAAANPC1 | |
| SCHEMBL4376768 | 0.75 | NAAA (0.52) | LMNAMAPK1TSHRNAAANPC1 | |
| SCHEMBL19118080 | 0.75 | HPGD (0.65) | LMNAMAPK1KMT2AHPGDCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |