Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.83 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.83 |
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.72 |
| ▸ | PDE3A | Q14432 | 4/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.72 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.66 |
| ▸ | CTSD | P07339 | 1/20 | 0.64 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.62 |
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | SI | P14410 | 1/20 | 0.61 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4053367 | 1.00 | CISD1 (0.83) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL22971872 | 0.91 | CISD1 (1.00) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL23496324 | 0.91 | CISD1 (1.00) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL23496323 | 0.91 | CISD1 (1.00) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL21263140 | 0.90 | CISD1 (1.00) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL1609551 | 0.90 | CISD1 (1.00) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL23496326 | 0.89 | ADAMTS5 (0.79) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL23496327 | 0.89 | ADAMTS5 (0.79) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL21263138 | 0.87 | CISD1 (1.00) | CISD1ADAMTS5MEN1KMT2APDE4B | |
| SCHEMBL4057761 | 0.85 | ADAMTS5 (0.75) | CISD1ADAMTS5MEN1KMT2APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |