Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.75 |
| ▸ | CISD1 | Q9NZ45 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 9/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057759 | 1.00 | ADAMTS5 (0.75) | ADAMTS5CISD1MEN1KMT2APDE4B | |
| SCHEMBL23496324 | 0.86 | CISD1 (1.00) | ADAMTS5CISD1MEN1KMT2APDE4B | |
| SCHEMBL22971872 | 0.86 | CISD1 (1.00) | ADAMTS5CISD1MEN1KMT2APDE4B | |
| SCHEMBL23496323 | 0.86 | CISD1 (1.00) | ADAMTS5CISD1MEN1KMT2APDE4B | |
| SCHEMBL4053367 | 0.85 | CISD1 (0.83) | ADAMTS5CISD1MEN1KMT2APDE4B | |
| SCHEMBL4053371 | 0.85 | CISD1 (0.83) | ADAMTS5CISD1MEN1KMT2APDE4B | |
| SCHEMBL21263140 | 0.85 | CISD1 (1.00) | ADAMTS5CISD1MEN1KMT2APDE4B | |
| SCHEMBL1609551 | 0.85 | CISD1 (1.00) | ADAMTS5CISD1MEN1KMT2APDE4B | |
| SCHEMBL4049607 | 0.84 | MMP13 (0.69) | ADAMTS5HPGD | |
| SCHEMBL4049602 | 0.84 | MMP13 (0.69) | ADAMTS5HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |