Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1073340 | 0.90 | CYP2C9 (0.54) | CYP2C9 | |
| SCHEMBL16035424 | 0.80 | RAF1 (0.54) | — | |
| SCHEMBL29427236 | 0.80 | RAF1 (0.54) | — | |
| SCHEMBL18988941 | 0.78 | BRAF (0.50) | — | |
| SCHEMBL3301142 | 0.78 | RAB9A (0.42) | GAALMNA | |
| SCHEMBL2887561 | 0.77 | BRAF (0.58) | LMNA | |
| SCHEMBL29536884 | 0.77 | BRAF (0.58) | LMNA | |
| SCHEMBL13644626 | 0.76 | LMNA (0.53) | GAALMNACYP2C9 | |
| SCHEMBL13643827 | 0.76 | CYP2C9 (0.63) | CYP2C9 | |
| SCHEMBL25421239 | 0.76 | RAF1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009030952-A2 | PHENYLCARBOXAMIDE DERIVATIVES AS INHIBITORS AND EFFECTORS OF THE HEDGEHOG PATHWAY | ASTRAZENECA AB (SE) | 2009-03-12 | — | — | WO | disclosed |