Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21495057 | 0.76 | IDO1 (0.37) | ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL166469 | 0.76 | IDO1 (0.37) | ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL38142 | 0.74 | ACP3 (0.39) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL5189721 | 0.74 | CYP3A4 (0.32) | — | |
| SCHEMBL168886 | 0.74 | ESR1 (0.45) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL1701143 | 0.74 | GABRA1 (0.46) | ALDH1A1 | |
| SCHEMBL22445608 | 0.74 | ACP3 (0.39) | ALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL20551403 | 0.74 | CES2 (0.40) | ALDH1A1CYP2C9 | |
| SCHEMBL166430 | 0.74 | CES2 (0.40) | ALDH1A1CYP2C9 | |
| SCHEMBL28855979 | 0.74 | GABRA1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017075341-A1 | FUSED IMIDAZOLE DERIVATIVES AS IDO/TDO INHIBITORS | SCIFLUOR LIFE SCIENCES, INC. (US) | 2017-05-04 | — | — | WO | disclosed |
| WO-2009123753-A1 | INHIBITION OF BACTERIAL BIOFILMS WITH IMIDAZOLE-PHENYL DERIVATIVES | NORTH CAROLINA STATE UNIVERSITY (US) | 2009-10-08 | — | — | WO | disclosed |