Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 3/20 | 0.53 |
| ▸ | CHRM1 known ✓ | P11229 | 3/20 | 0.53 |
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.53 |
| ▸ | CHRM5 known ✓ | P08912 | 2/20 | 0.53 |
| ▸ | CHRM3 known ✓ | P20309 | 2/20 | 0.53 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.53 |
| ▸ | OPRM1 known ✓ | P35372 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5293966 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5818944 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5286365 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5299321 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5303290 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5818381 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5295014 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5293872 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5294037 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 | |
| SCHEMBL5814661 | 0.98 | TP53 (0.61) | KMT2ATP53MEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824804-A4 | ION PAIR AMPHIPHILES AS HYDRATE INHIBITORS | NALCO CO (US) | 2009-03-04 | — | — | EP | claimed |
| US-20080064611-A1 | ION PAIR AMPHIPHILES AS HYDRATE INHIBITORS | ECOLAB USA INC. | 2008-03-13 | — | — | US | claimed |
| EP-1824804-A2 | ION PAIR AMPHIPHILES AS HYDRATE INHIBITORS | Nalco Company (US) | 2007-08-29 | — | — | EP | claimed |
| WO-2006052455-A2 | ION PAIR AMPHIPHILES AS HYDRATE INHIBITORS | NALCO COMPANY (US) | 2006-05-18 | — | — | WO | claimed |
| US-20060094913-A1 | Ion pair amphiphiles as hydrate inhibitors | NALCO ENERGY SERVICES | 2006-05-04 | — | — | US | claimed |
| EP-1824804-A4 | ION PAIR AMPHIPHILES AS HYDRATE INHIBITORS | NALCO CO (US) | 2009-03-04 | — | — | EP | disclosed |
| US-20080064611-A1 | ION PAIR AMPHIPHILES AS HYDRATE INHIBITORS | ECOLAB USA INC. | 2008-03-13 | — | — | US | disclosed |
| EP-1824804-A2 | ION PAIR AMPHIPHILES AS HYDRATE INHIBITORS | Nalco Company (US) | 2007-08-29 | — | — | EP | disclosed |
| WO-2006052455-A2 | ION PAIR AMPHIPHILES AS HYDRATE INHIBITORS | NALCO COMPANY (US) | 2006-05-18 | — | — | WO | disclosed |
| US-20060094913-A1 | Ion pair amphiphiles as hydrate inhibitors | NALCO ENERGY SERVICES | 2006-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060094913-A1 | Ion pair amphiphiles as hydrate inhibitors | AQP1, AQP4, AQP3 | CHRM2 4620/4885CHRM1 4570/4885ACHE 2311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.