Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.79 |
| ▸ | NCF1 | P14598 | 3/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Quinaldine SCHEMBL11103776 | 0.91 | CYP1A2 (0.86) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL29124097 | 0.89 | CYP1A2 (0.91) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL29405077 | 0.89 | CYP1A2 (1.00) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL5428195 | 0.89 | CYP1A2 (1.00) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL56360 | 0.89 | CYP1A2 (1.00) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL27277314 | 0.88 | CYP1A2 (0.79) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL10348815 | 0.87 | CYP1A2 (0.95) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL9724469 | 0.87 | CYP1A2 (0.95) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL4432999 | 0.87 | CYP1A2 (0.95) | CYP1A2NCF1NOS2BACE1CA12 | |
| Quinaldine SCHEMBL22129966 | 0.87 | CYP1A2 (0.95) | CYP1A2NCF1NOS2BACE1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247579-A1 | 2-[3H-THIAZOL-2-YLIDINEMETHYL]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED | 2009-10-01 | — | — | US | disclosed |
| EP-2029584-A2 | 2-[3H-THIAZOL-2-YLIDINEMETHYL]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE | Cancer Research Technology Limited (GB) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007096618-A2 | 2-[3H-THIAZOL-2-YLIDINEMETHYL]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-08-30 | — | — | WO | disclosed |
| CN-1882307-A | Method for dyeing fibres containing keratine | HENKEL KGAA (DE) | 2006-12-20 | — | — | CN | disclosed |
| CN-1761517-A | Mixing device | HENKEL KGAA (DE) | 2006-04-19 | — | — | CN | disclosed |
| US-6149895-A | Dental bleaching compositions, kits & methods | KREATIV, INC (US) | 2000-11-21 | — | — | US | disclosed |
| EP-0383092-B1 | Chromogenic merocyanine enzyme substrates | BAYER AG (US) | 1995-12-13 | — | — | EP | disclosed |
| US-5382497-A | Optical recording medium and process for recording thereupon | CANON KABUSHIKI KAISHA (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5320930-A | Irradiating to form detectable pits; containing pyrylium, cyanine, merocyanine dyes, selenapyrylium and methine dyes | CANON KABUSHIKI KAISHA (JP) | 1994-06-14 | — | — | US | disclosed |
| US-5278026-A | Comprising photosensitive compounds | CANON KABUSHIKI KAISHA (JP) | 1994-01-11 | — | — | US | disclosed |
| US-5246814-A | Mehtine or pyrylium dye | CANON KABUSHIKI KAISHA (JP) | 1993-09-21 | — | — | US | disclosed |
| US-5191073-A | Indicators for colorimetric analysis of enzymes | MILES INC. (US) | 1993-03-02 | — | — | US | disclosed |
| US-5122602-A | Optical indicators; medical diagnosis; quantitative analysis; immunoassay | MILES INC. (US) | 1992-06-16 | — | — | US | disclosed |
| US-5079127-A | Methine Dyes | CANON KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| US-5079128-A | Thin film containing a methine dye having at least two dimethylaminophenyl groups and a carbonium ion; laser writing; heat resistance | CANON KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |
| EP-0383092-A2 | Chromogenic merocyanine enzyme substrates | Bayer Corporation (US) | 1990-08-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247579-A1 | 2-[3H-THIAZOL-2-YLIDINEMETHYL]PYRIDINES AND RELATED COMPOUNDS AND THEIR USE | RB1, RBBP5, RRM2B | CYP1A2 2027/4885NCF1 1802/4885NOS2 2096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.