Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKT1 | P31749 | 7/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SCD | O00767 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21144279 | 0.87 | ALDH1A1 (0.47) | AKT1PDPK1ABCB11AKT2GAB1 | |
| SCHEMBL5556928 | 0.85 | ALDH1A1 (0.44) | KMT2AAKT1PDPK1ABCB11AKT2 | |
| SCHEMBL4660784 | 0.80 | — | — | |
| SCHEMBL25006980 | 0.72 | POLB (0.35) | MAPTKMT2ACES1AKT1ALDH1A1 | |
| SCHEMBL21044689 | 0.70 | KMT2A (0.80) | MAPTKMT2ACES1ALDH1A1 | |
| SCHEMBL23530133 | 0.70 | KMT2A (0.80) | MAPTKMT2ACES1ALDH1A1 | |
| SCHEMBL23530132 | 0.70 | KMT2A (0.80) | MAPTKMT2ACES1ALDH1A1 | |
| SCHEMBL21044653 | 0.70 | KMT2A (0.80) | MAPTKMT2ACES1ALDH1A1 | |
| SCHEMBL21044669 | 0.70 | KMT2A (0.80) | MAPTKMT2ACES1ALDH1A1 | |
| SCHEMBL23748450 | 0.70 | KMT2A (0.80) | MAPTKMT2ACES1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1549624-B1 | INHIBITORS OF FATTY ACID AMIDE HYDROLASE | SCRIPPS RESEARCH INST (US) | 2009-05-13 | — | — | EP | disclosed |