Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 7/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | AKT2 | P31751 | 1/20 | 0.42 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.42 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11499173 | 0.98 | ALDH1A1 (0.47) | ALDH1A1AKT1PDPK1ABCB11AKT2 | |
| SCHEMBL11149825 | 0.98 | ALDH1A1 (0.47) | ALDH1A1AKT1PDPK1ABCB11AKT2 | |
| SCHEMBL21144279 | 0.98 | ALDH1A1 (0.47) | ALDH1A1AKT1PDPK1ABCB11AKT2 | |
| SCHEMBL4660784 | 0.94 | — | — | |
| SCHEMBL4054411 | 0.85 | MAPT (0.43) | ALDH1A1AKT1PDPK1ABCB11AKT2 | |
| SCHEMBL14401558 | 0.85 | — | — | |
| SCHEMBL2010135 | 0.77 | — | — | |
| SCHEMBL1101930 | 0.75 | — | — | |
| SCHEMBL4219953 | 0.72 | CES1 (0.49) | ALDH1A1TSHR | |
| SCHEMBL2006039 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | claimed |
| WO-2005027856-A2 | INHIBITORS OF ANTHRAX LETHAL FACTOR | CENGENT THERAPEUTICS (US) | 2005-03-31 | — | — | WO | claimed |
| CN-116622432-A | Motor vehicle brake fluid and preparation method and application thereof | 中国石油化工股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| US-20230025130-A1 | METHODS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-26 | — | — | US | disclosed |
| US-11129829-B2 | Methods for modulating splicing | SKYHAWK THERAPEUTICS, INC. (US) | 2021-09-28 | — | — | US | disclosed |
| US-20200390765-A1 | METHODS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2020-12-17 | — | — | US | disclosed |
| US-10737280-B2 | Method of using flotation collector containing azolethione structure | CENTRAL SOUTH UNIVERSITY (CN) | 2020-08-11 | — | — | US | disclosed |
| US-20190217310-A1 | METHOD OF USING FLOTATION COLLECTOR CONTAINING AZOLETHIONE STRUCTURE | CENTRAL SOUTH UNIVERSITY (CN) | 2019-07-18 | — | — | US | disclosed |
| US-20080280836-A1 | Anti-hypercholesterolemic biaryl azetidinone compounds | MORRIELLO GREGORI J | 2008-11-13 | — | — | US | disclosed |
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | CENGENT THERAPEUTICS (US) | 2007-08-23 | — | — | US | disclosed |
| WO-2005027856-A2 | INHIBITORS OF ANTHRAX LETHAL FACTOR | CENGENT THERAPEUTICS (US) | 2005-03-31 | — | — | WO | disclosed |
| EP-0502110-B1 | (HETERO) 4-ARYLMETHOXY PHENYL DIAZOLE DERIVATIVES, METHOD FOR PREPARING SAME, AND THEIR THERAPEUTICAL APPLICATIONS | SYNTHELABO (FR) | 1995-02-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280836-A1 | Anti-hypercholesterolemic biaryl azetidinone compounds | APOB, PCSK9, CYP46A1 | ALDH1A1 1045/4885AKT1 1237/4885PDPK1 4176/4885 |
| US-11129829-B2 | Methods for modulating splicing | RBM17, SNRPE, SNRPB2 | ALDH1A1 3474/4885AKT1 2455/4885PDPK1 2728/4885 |
| US-20230025130-A1 | METHODS FOR MODULATING SPLICING | RBM17, SNRPE, SNRPB2 | ALDH1A1 3474/4885AKT1 2455/4885PDPK1 2728/4885 |
| US-20070197577-A1 | Inhibitors of anthrax lethal factor | APAF1, ANTXR2, LITAF | ALDH1A1 4059/4885AKT1 1215/4885PDPK1 2712/4885 |
| US-20200390765-A1 | METHODS FOR MODULATING SPLICING | RBM17, SNRPE, SNRPB2 | ALDH1A1 3474/4885AKT1 2455/4885PDPK1 2728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.