SCHEMBL4054789

SCHEMBL4054789

[c]1cncc2cncnc12

nearest known ligand 0.37

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EGFR P00533 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20483 0.71 EGFR (0.47) EGFR
SCHEMBL276736 0.71 KDM4E (0.38) EGFR
SCHEMBL3936126 0.67
SCHEMBL2393986 0.64
SCHEMBL8874014 0.64 EGFR (0.58) EGFR
SCHEMBL8311252 0.62 EGFR (0.38) EGFR
SCHEMBL3934464 0.62 EGFR (0.38) EGFR
SCHEMBL140301 0.62 EGFR (0.46) EGFR
SCHEMBL29809882 0.62 EGFR (0.46) EGFR
SCHEMBL3936319 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2017264-A1 Substituted phenyl propargyl compounds, method for their manufacture and their use as herbicides and plant growth regulators BAYER CROPSCIENCE AG (DE) 2009-01-21 EP disclosed