Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 1/20 | 0.67 |
| ▸ | MAX | P61244 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | MMP3 | P08254 | 1/20 | 0.50 |
| ▸ | MMP13 | P45452 | 1/20 | 0.50 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4054876 | 1.00 | MYC (0.67) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4053705 | 0.95 | ALOX5 (0.64) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4053703 | 0.95 | ALOX5 (0.64) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4054061 | 0.89 | MYC (0.65) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4054059 | 0.89 | MYC (0.65) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4058214 | 0.89 | MYC (0.65) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4058211 | 0.89 | MYC (0.65) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4057966 | 0.89 | MYC (0.65) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4056061 | 0.89 | MYC (0.81) | MYCMAXALDH1A1MAPTGAA | |
| SCHEMBL4057962 | 0.89 | MYC (0.65) | MYCMAXALDH1A1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |