Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056044 | 0.86 | CXCR2 (0.35) | CXCR2CX3CR1 | |
| SCHEMBL4119767 | 0.68 | CXCR2 (0.60) | CXCR2CX3CR1 | |
| SCHEMBL4119760 | 0.68 | CXCR2 (0.60) | CXCR2CX3CR1 | |
| SCHEMBL212299 | 0.56 | CXCR2 (0.71) | CXCR2CX3CR1 | |
| SCHEMBL12022718 | 0.56 | CXCR2 (0.71) | CXCR2CX3CR1 | |
| SCHEMBL1588259 | 0.54 | CX3CR1 (0.35) | CXCR2CX3CR1 | |
| SCHEMBL17904270 | 0.49 | RPS6KA3 (0.37) | CXCR2 | |
| SCHEMBL8663220 | 0.48 | RPS6KA3 (0.32) | — | |
| SCHEMBL24443109 | 0.44 | AAK1 (0.31) | — | |
| Isopropyl Alcohol SCHEMBL4890549 | 0.44 | ALDH1A1 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009120140-A1 | NOVEL 5,7-DISUBSTITUTED [1,3]THIAZOLO[4,5-D]PYRIMIDIN-2(3H)-ONE DERIVATIVES 258 | ASTRAZENECA AB (SE) | 2009-10-01 | — | — | WO | claimed |