Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4063745 | 0.89 | PKM (0.41) | EPHX2PKMDPP4 | |
| SCHEMBL4059154 | 0.84 | GRIN1 (0.42) | EPHX2 | |
| SCHEMBL3846074 | 0.82 | DPP4 (0.35) | PKMDPP4 | |
| SCHEMBL4055534 | 0.76 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL4449687 | 0.74 | GRIN1 (0.48) | EPHX2 | |
| SCHEMBL4064627 | 0.73 | PKM (0.41) | EPHX2PKM | |
| SCHEMBL987284 | 0.72 | PKM (0.41) | PKMDPP4 | |
| SCHEMBL28488613 | 0.72 | TSHR (0.40) | EPHX2 | |
| SCHEMBL4057608 | 0.72 | PKM (0.52) | PKMDPP4 | |
| SCHEMBL3843113 | 0.70 | PKM (0.40) | PKMDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030248-A1 | Ethynylphenylbiadamantane derivatives | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2009-01-29 | — | — | US | disclosed |
| EP-2014636-A1 | Ethynylphenylbiadamantane derivatives | Daicel Chemical Industries, Ltd. (JP) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030248-A1 | Ethynylphenylbiadamantane derivatives | CHRNA5, CHRNE, ADRA1D | EPHX2 2237/4885PKM 4221/4885DPP4 2292/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.