SCHEMBL4055015

SCHEMBL4055015

Cc1c(O)ccc(C(C)(C)c2ccc(O)cc2)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 11/20 0.54
ESR2 Q92731 8/20 0.54
HSD17B10 Q99714 3/20 0.54
CYP3A4 P08684 2/20 0.54
HPGD P15428 2/20 0.54
AR P10275 1/20 0.54
TSHR P16473 1/20 0.54
SLC6A2 P23975 1/20 0.54
SLC6A4 P31645 1/20 0.54
HTR6 P50406 1/20 0.54
ESRRG P62508 1/20 0.54
SLC6A3 Q01959 1/20 0.54
ALDH1A1 P00352 3/20 0.47
LMNA P02545 2/20 0.43
TYR P14679 2/20 0.43
SENP1 Q9P0U3 1/20 0.39
ALOX15 P16050 3/20 0.38
NR1I2 O75469 1/20 0.38
CYP2C9 P11712 1/20 0.38
MIF P14174 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4055665 0.94 ESR1 (0.47) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL29375143 0.85 ESR1 (0.58) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL759290 0.85 ESR1 (0.58) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL4056187 0.84 ESR1 (0.41) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL13589380 0.81 ESR1 (0.54) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL13609967 0.81 ESR1 (0.58) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL4063769 0.80 ESR1 (0.47) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL1224410 0.79 ESR1 (0.43) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL6751257 0.78 ESR1 (0.46) ESR1ESR2HSD17B10CYP3A4HPGD
SCHEMBL6157236 0.76 ESR1 (0.62) ESR1ESR2HSD17B10CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM ESR1 392/4885ESR2 895/4885HSD17B10 3699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.