⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL310152 | 1.00 | — | — | |
| SCHEMBL4058686 | 1.00 | ALDH1A1 (0.44) | — | |
| SCHEMBL2917452 | 0.97 | — | — | |
| SCHEMBL5932598 | 0.88 | ALDH1A1 (0.36) | — | |
| SCHEMBL1498139 | 0.87 | — | — | |
| SCHEMBL5932760 | 0.86 | ALDH1A1 (0.34) | — | |
| SCHEMBL16146175 | 0.84 | MEN1 (0.38) | — | |
| SCHEMBL1469742 | 0.84 | MEN1 (0.38) | — | |
| SCHEMBL2515564 | 0.83 | ALDH1A1 (0.55) | — | |
| SCHEMBL2513750 | 0.83 | ALDH1A1 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
| US-20160039879-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. (US) | 2016-02-11 | — | — | US | disclosed |
| EP-2968445-A2 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | Su, Zhuang (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014145686-A2 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | SU ZHUANG (US) | 2014-09-18 | — | — | WO | disclosed |
| WO-2014145686-A2 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | SU ZHUANG (US) | 2014-09-18 | — | — | WO | disclosed |
| US-20090042745-A1 | BIOSENSOR CHIP | FUJIFILM CORPORATION (JP) | 2009-02-12 | — | — | US | disclosed |
| EP-2023140-A1 | Biosensor chip | FUJIFILM Corporation (JP) | 2009-02-11 | — | — | EP | disclosed |
| WO-2007066496-A1 | BENZOYLUREA COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-14 | — | — | WO | disclosed |