SCHEMBL1469742

SCHEMBL1469742

COCCOCCOCCOCCCCCCCCCCCS

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
THRB P10828 1/20 0.38
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.38
CA2 P00918 1/20 0.36
HDAC3 O15379 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC1 Q13547 1/20 0.35
HDAC7 Q8WUI4 1/20 0.35
HDAC2 Q92769 1/20 0.35
HDAC10 Q969S8 1/20 0.35
HDAC11 Q96DB2 1/20 0.35
HDAC8 Q9BY41 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35
HDAC9 Q9UKV0 1/20 0.35
HDAC5 Q9UQL6 1/20 0.35
EPHX2 P34913 2/20 0.34
ALDH1A1 P00352 1/20 0.33
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16146175 1.00 MEN1 (0.38) MEN1THRBHTTKMT2AMAPT
SCHEMBL5932402 0.97 MEN1 (0.34) MEN1THRBHTTKMT2AMAPT
SCHEMBL5932598 0.90 ALDH1A1 (0.36) MEN1THRBHTTKMT2AMAPT
SCHEMBL5911546 0.90
SCHEMBL14891066 0.90 CYP3A4 (0.34) MEN1THRBHTTKMT2AMAPT
SCHEMBL5932760 0.87 ALDH1A1 (0.34) MEN1THRBHTTKMT2AMAPT
SCHEMBL12754636 0.87 MEN1 (0.46) MEN1THRBHTTKMT2AMAPT
SCHEMBL12762784 0.87 MEN1 (0.46) MEN1THRBHTTKMT2AMAPT
SCHEMBL12924152 0.87 MEN1 (0.46) MEN1THRBHTTKMT2AMAPT
SCHEMBL5933045 0.84 ALDH1A1 (0.36) MEN1THRBHTTKMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2773958-B1 A METHOD OF IDENTIFYING AN ANALYTE IN A BIOLOGICAL SAMPLE UNIV CAPE TOWN (ZA) 2017-11-29 EP disclosed
US-9518986-B2 Method of detecting and/or quantifying an analyte in a biological sample UNIVERSITY OF CAPE TOWN (ZA) 2016-12-13 US disclosed
US-20140302492-A1 METHOD OF DETECTING AND/OR QUALIFYING AN ANALYTE IN A BIOLOGICAL SAMPLE UNIVERSITY OF CAPE TOWN (ZA) 2014-10-09 US disclosed
EP-2047259-B1 BIOSENSOR COMPRISING INTERDIGITATED ELECTRODE SENSOR UNITS KOREA RES INST OF STANDARDS (KR) 2012-04-18 EP disclosed
US-20110070659-A1 SAMPLE PRESENTATION DEVICE QIAGEN SCIENCES, INC. (DE) 2011-03-24 US disclosed
US-20110070659-A1 SAMPLE PRESENTATION DEVICE QIAGEN SCIENCES, INC. (DE) 2011-03-24 US disclosed
US-20090163380-A1 ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY STRATOS BIOSYSTEMS, LLC (US) 2009-06-25 US disclosed
US-20090084686-A1 Biosensor comprising interdigitated electrode sensor units KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE (KR) 2009-04-02 US disclosed
US-20080248589-A1 Sample Presentation Device LUMICYTE, INC. 2008-10-09 US disclosed
US-20080248589-A1 Sample Presentation Device LUMICYTE, INC. 2008-10-09 US disclosed
EP-1756543-A2 SAMPLE PRESENTATION DEVICE Qiagen Sciences, Inc. (US) 2007-02-28 EP disclosed
WO-2005114132-A2 SAMPLE PRESENTATION DEVICE QIAGEN SCIENCES, INC. (DE) 2005-12-01 WO disclosed
US-20050164402-A1 Sample presentation device QLAGEN SCIENCES, INC. (DE) 2005-07-28 US disclosed
US-6290331-B1 High efficiency orifice plate structure and printhead using the same HEWLETT-PACKARD COMPANY 2001-09-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090163380-A1 ANALYTE FOCUSING BIOCHIPS FOR AFFINITY MASS SPECTROMETRY STUB1, SPR, DBI MEN1 2423/4885THRB 1624/4885HTT 4143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.