Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.73 |
| ▸ | OGFRL1 | Q5TC84 | 13/20 | 0.73 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.57 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL4059045 | 0.91 | OPRM1 (0.62) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL4046708 | 0.89 | OPRM1 (0.68) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL681592 | 0.84 | OPRM1 (1.00) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4047154 | 0.81 | OPRM1 (0.56) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL4053432 | 0.81 | OPRM1 (0.59) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Citric Acid SCHEMBL4047655 | 0.77 | OPRM1 (0.53) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL3407050 | 0.74 | OPRM1 (0.80) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Citric Acid SCHEMBL4054564 | 0.74 | OPRM1 (0.47) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL4050797 | 0.74 | OPRM1 (0.55) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL13805869 | 0.73 | OPRM1 (0.73) | OPRM1OGFRL1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1697379-B1 | SPIROCYCLIC CYCLOHEXANE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2009-03-25 | — | — | EP | claimed |