Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRK6 | P43250 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | HSD17B14 | Q9BPX1 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28005102 | 0.81 | BCAT1 (0.38) | GRK6IDO1MAPK1DCUN1D1NOTUM | |
| SCHEMBL2277157 | 0.81 | IDO1 (0.53) | IDO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL30497931 | 0.81 | IDO1 (0.53) | IDO1CASP3SENP8SENP7SENP6 | |
| SCHEMBL6287518 | 0.79 | IDO1 (0.36) | IDO1SMN1; SMN2NPSR1ALOX15KDM4E | |
| SCHEMBL23451813 | 0.77 | NOTUM (0.49) | IDO1ERN1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3391917 | 0.77 | MEN1 (0.31) | MEN1KMT2A | |
| SCHEMBL3848065 | 0.75 | F2RL3 (0.37) | IDO1LMNA | |
| SCHEMBL7242035 | 0.75 | AR (0.47) | GRK6ARF2F10PLG | |
| SCHEMBL674356 | 0.74 | NISCH (0.42) | MAPTSMN1; SMN2HPGDMEN1KMT2A | |
| SCHEMBL30589021 | 0.74 | NISCH (0.42) | MAPTSMN1; SMN2HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009119880-A1 | SUBSTITUTED PYRAZOLE DERIVATIVES AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-10-01 | — | — | WO | disclosed |