Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TYMP | P19971 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30589021 | 1.00 | NISCH (0.42) | NISCHKDM4EMEN1KMT2AGSK3B | |
| SCHEMBL27596511 | 1.00 | NISCH (0.42) | NISCHKDM4EMEN1KMT2AGSK3B | |
| SCHEMBL28421923 | 0.85 | ALDH1A1 (0.33) | MEN1KMT2AGSK3BCDK5CDK5R1 | |
| SCHEMBL27373163 | 0.84 | GSK3B (0.36) | NISCHKDM4EMEN1KMT2AGSK3B | |
| SCHEMBL28955029 | 0.83 | DNMT1 (0.44) | NISCHKDM4EMEN1KMT2AGSK3B | |
| SCHEMBL27762988 | 0.81 | KDM4E (0.35) | NISCHKDM4EMEN1KMT2AGSK3B | |
| SCHEMBL27628456 | 0.80 | KMT2A (0.47) | KDM4EMEN1KMT2AGSK3BCDK5 | |
| SCHEMBL11852245 | 0.80 | CYP1A2 (0.47) | KDM4EMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL26905316 | 0.76 | POLB (0.40) | NISCHKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3252001 | 0.76 | IDO1 (0.55) | KDM4EMEN1KMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233766-B | Naphthalene ring-pyrazole compound and preparation method and application thereof | 贵州医科大学 | 2022-07-01 | — | — | CN | claimed |
| CN-111233766-A | Naphthalene ring-pyrazole compound and preparation method and application thereof | 贵州医科大学 | 2020-06-05 | — | — | CN | claimed |
| US-8053090-B2 | Phosphorescent multinuclear copper complex and organic electroluminescent device using the same | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2011-11-08 | — | — | US | claimed |
| US-8039123-B2 | Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same | SAMSUNG MOBILE DISPLAY CO., LTD. (KR) | 2011-10-18 | — | — | US | claimed |
| US-20070267959-A1 | Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2007-11-22 | — | — | US | claimed |
| US-20070270592-A1 | Phosphorescent multinuclear copper complex and organic electroluminescent device using the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2007-11-22 | — | — | US | claimed |
| CN-101074237-A | Phosphorescent multinuclear copper complex and organic electroluminescent device using the same | SAMSUNG SDI CO LTD (KR) | 2007-11-21 | — | — | CN | claimed |
| US-7294415-B2 | Organometallic complex and organic electroluminescent device employing the same | SAMSUNG SDI CO., LTD. (KR) | 2007-11-13 | — | — | US | claimed |
| US-20040265633-A1 | Organometallic complex and organic electroluminescent device employing the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2004-12-30 | — | — | US | claimed |
| US-20250281465-A1 | MOLECULES THAT ENHANCE EXTRACELLULAR VESICLE RELEASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2025-09-11 | — | — | US | disclosed |
| US-20230272401-A1 | COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF | Genetic Intelligence, Inc | 2023-08-31 | — | — | US | disclosed |
| CN-107801390-B | Process for the manufacture of 1-cyclopropylnaphthalene | 帕西昂奥地利有限两合公司 | 2021-12-21 | — | — | CN | disclosed |
| US-10683245-B2 | Process for manufacturing 1-cyclopropyl-naphthalenes | PATHEON AUSTRIA GMBH & CO. KG (AT) | 2020-06-16 | — | — | US | disclosed |
| CN-107382782-B | Method for synthesizing polyaryl substituted naphthol derivative | 绍兴文理学院 | 2020-05-12 | — | — | CN | disclosed |
| US-20030073218-A1 | High affinity inhibitors for target validation and uses thereof | PRINCETON UNIVERSITY | 2003-04-17 | — | — | US | disclosed |
| US-6383790-B1 | PYRAZOLO(3,4-D)PYRIMIDINE BASED COMPOUND; ANTICARCINOGENIC AGENTS; ANTITUMOR AGENTS | PRINCETON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |
| EP-1140938-A2 | HIGH AFFINITY INHIBITORS FOR TARGET VALIDATION AND USES THEREOF | Princeton University (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000042042-A2 | HIGH AFFINITY INHIBITORS FOR TARGET VALIDATION AND USES THEREOF | PRINCETON UNIVERSITY (US) | 2000-07-20 | — | — | WO | disclosed |
| US-5202218-A | Diffusion transfer | MITSUBISHI PAPER MILLS LIMITED (JP) | 1993-04-13 | — | — | US | disclosed |
| US-4873170-A | EXPOSURE OF EMULSION LAYER CONTAINING SENSITIZING DYE; SCUM FREE | MITSUBISHI PAPER MILLS, LTD. (JP) | 1989-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070267959-A1 | Phosphorescent heteronuclear copper(I)-iridium(III) complex and organic electroluminescence device using the same | ORC3, AP3M1, PUF60 | NISCH 574/4885KDM4E 3707/4885MEN1 873/4885 |
| US-20040265633-A1 | Organometallic complex and organic electroluminescent device employing the same | TYR, CYBA, LAGE3 | NISCH 265/4885KDM4E 2310/4885MEN1 2363/4885 |
| US-20230272401-A1 | COMPOSITIONS FOR FLCN GENE MODULATION AND METHODS THEREOF | TARDBP, FUS, RBM17 | NISCH 4836/4885KDM4E 2645/4885MEN1 4364/4885 |
| US-20250281465-A1 | MOLECULES THAT ENHANCE EXTRACELLULAR VESICLE RELEASE | ORAI1, CHERP, CASR | NISCH 4295/4885KDM4E 3336/4885MEN1 2803/4885 |
| US-10683245-B2 | Process for manufacturing 1-cyclopropyl-naphthalenes | KCNK17, CYP1B1, BCKDK | NISCH 100/4885KDM4E 595/4885MEN1 1417/4885 |
| US-20030073218-A1 | High affinity inhibitors for target validation and uses thereof | SRC, MARCKS, TEC | NISCH 3989/4885KDM4E 1129/4885MEN1 3818/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.