Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 6/20 | 0.40 |
| ▸ | DAO | P14920 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10440205 | 0.88 | LTB4R (0.52) | LTB4R | |
| SCHEMBL18995061 | 0.76 | CYP2A6 (0.36) | CYP2A6MEN1LMNATHRBBLM | |
| SCHEMBL17428932 | 0.76 | CYP2A6 (0.36) | CYP2A6MEN1LMNATHRBBLM | |
| SCHEMBL19222446 | 0.75 | CYP2A6 (0.38) | CYP2A6MEN1LMNATHRBBLM | |
| SCHEMBL4054148 | 0.71 | LTB4R (0.40) | LTB4RDAOKMT2AFFAR1GPR52 | |
| SCHEMBL13147505 | 0.71 | LTB4R (0.50) | LTB4RDAOFFAR1 | |
| SCHEMBL2082912 | 0.71 | HIF1A (0.40) | CYP2A6THRBTDP1 | |
| SCHEMBL6964424 | 0.71 | — | — | |
| SCHEMBL8255788 | 0.70 | TP53 (0.36) | DAOMEN1LMNAKMT2ATDP1 | |
| SCHEMBL14116384 | 0.70 | DAO (0.37) | DAOFFAR1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057162-A2 | FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | Sepracor Inc. (US) | 2009-05-13 | — | — | EP | disclosed |
| WO-2008005456-A2 | FUSED HETEROCYCLIC INHIBITORS OF D-AMINO ACID OXIDASE | SEPRACOR INC. (US) | 2008-01-10 | — | — | WO | disclosed |