Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | HTT | P42858 | 5/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | RECQL | P46063 | 2/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4055383 | 1.00 | ALDH1A1 (0.60) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL4049726 | 0.84 | MAPT (0.52) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL4049720 | 0.84 | MAPT (0.52) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL4052733 | 0.83 | MAPT (0.57) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL4052735 | 0.83 | MAPT (0.57) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL5946453 | 0.82 | MAPT (0.77) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL4053914 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL4053916 | 0.80 | ALDH1A1 (0.48) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL1880405 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTGAAHPGD | |
| SCHEMBL1880407 | 0.80 | ALDH1A1 (0.58) | ALDH1A1MAPTHTTGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111260-A1 | PHENYLSULFONAMIDE-SUBSTITUTED, PYRAZOLO[1, 5-A]PYRIMIDINES, METHODS FOR PREPARATION AND USES THEREOF | WYETH (US) | 2009-09-11 | — | — | WO | disclosed |