Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3714616 | 0.78 | ALDH1A1 (0.39) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL10760096 | 0.78 | NPC1 (0.36) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL1559313 | 0.76 | CCR1 (0.35) | RAB9ACHRM1 | |
| SCHEMBL2734403 | 0.75 | NPC1 (0.37) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL3373922 | 0.75 | MEN1 (0.35) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL9008263 | 0.75 | ALDH1A1 (0.42) | MEN1KMT2ACHRM1ALDH1A1POLB | |
| SCHEMBL4210086 | 0.74 | PTGS1 (0.45) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL10401677 | 0.73 | ALDH1A1 (0.33) | MEN1KMT2ANPC1MITFRAB9A | |
| SCHEMBL18926950 | 0.73 | SLC6A2 (0.36) | MEN1KMT2ACHRM1ALDH1A1POLB | |
| SCHEMBL8448450 | 0.73 | HTR2A (0.40) | MEN1KMT2ACHRM1ALDH1A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599726-A4 | SELECTIVE MODULATION OF TLR-MEDIATED BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES CO (US) | 2009-07-22 | — | — | EP | disclosed |
| EP-1599726-A2 | SELECTIVE MODULATION OF TLR-MEDIATED BIOLOGICAL ACTIVITY | 3M Innovative Properties Company (US) | 2005-11-30 | — | — | EP | disclosed |
| WO-2004075865-A2 | SELECTIVE MODULATION OF TLR-MEDIATED BIOLOGICAL ACTIVITY | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2004-09-10 | — | — | WO | disclosed |