Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CDK4 | P11802 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9008263 | 0.85 | ALDH1A1 (0.42) | ALDH1A1POLBMEN1KMT2AHTR2A | |
| SCHEMBL2734403 | 0.82 | NPC1 (0.37) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15422618 | 0.82 | DRD2 (0.43) | ALDH1A1MEN1KMT2AHTR2AADRA2B | |
| SCHEMBL19436608 | 0.81 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| SCHEMBL10760096 | 0.81 | NPC1 (0.36) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL18926950 | 0.80 | SLC6A2 (0.36) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10401677 | 0.80 | ALDH1A1 (0.33) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7835140 | 0.80 | ALDH1A1 (0.41) | ALDH1A1POLBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9158087 | 0.80 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2MAPT | |
| Bromide SCHEMBL1169843 | 0.79 | POLB (0.33) | ALDH1A1POLBMEN1KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12559453-B2 | Sulfonic acid-modified polyisocyanate and preparation method therefor | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2026-02-24 | — | — | US | claimed |
| EP-4144780-B1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | WANHUA CHEMICAL GROUP CO LTD (CN) | 2025-12-24 | — | — | EP | claimed |
| CN-115466201-B | Sulfonic acid modified polyisocyanate and preparation method thereof | 万华化学集团股份有限公司 | 2024-05-03 | — | — | CN | claimed |
| US-20230257344-A1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2023-08-17 | — | — | US | claimed |
| EP-4144780-A1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | Wanhua Chemical Group Co., Ltd. (CN) | 2023-03-08 | — | — | EP | claimed |
| WO-2022257585-A1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | 万华化学集团股份有限公司 | 2022-12-15 | — | — | WO | claimed |
| CN-115466201-A | Sulfonic acid modified polyisocyanate and preparation method thereof | 万华化学集团股份有限公司 | 2022-12-13 | — | — | CN | claimed |
| US-12559453-B2 | Sulfonic acid-modified polyisocyanate and preparation method therefor | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2026-02-24 | — | — | US | disclosed |
| EP-4144780-B1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | WANHUA CHEMICAL GROUP CO LTD (CN) | 2025-12-24 | — | — | EP | disclosed |
| CN-114752031-B | Aqueous hardener, aqueous matting coating composition containing same and related applications | 长兴材料工业（广东）有限公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-115466201-B | Sulfonic acid modified polyisocyanate and preparation method thereof | 万华化学集团股份有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-116875262-A | Pressure-sensitive adhesive composition, application thereof and method for preparing polyurethane | 长兴材料工业（广东）有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230257344-A1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | WANHUA CHEMICAL GROUP CO., LTD. (CN) | 2023-08-17 | — | — | US | disclosed |
| CN-105745210-A | Process for the preparation of 8-(4-aminophenoxy)-4h-pyrido[2,3-b]pyrazin-3-one derivatives | 癌症研究技术有限公司 | 2016-07-06 | — | — | CN | disclosed |
| WO-2015075482-A1 | PROCESS FOR THE PREPARATION OF 8-(4-AMINOPHENOXY)-4H-PYRIDO[2,3-B]PYRAZIN-3-ONE DERIVATIVES | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2015-05-28 | — | — | WO | disclosed |
| WO-2010106099-A1 | ELECTROCHEMICAL FLOW CELL DETECTOR | UNIVERSITY OF COPENHAGEN (DK) | 2010-09-23 | — | — | WO | disclosed |
| WO-2005025745-A1 | METHOD FOR THE INSERTION OF ACRYLONITRILE IN A METAL-CARBON BOND | LANXESS DEUTSCHLAND GMBH (DE) | 2005-03-24 | — | — | WO | disclosed |
| US-20050059812-A1 | Process for insertion of acrylonitrile into a metal-carbon bond | LANXESS DEUTSCHLAND GMBH (DE) | 2005-03-17 | — | — | US | disclosed |
| US-4594303-A | Containing charge generating and charge transfer material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-06-10 | — | — | US | disclosed |
| US-4450219-A | CHARGE GENERATING COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1984-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230257344-A1 | SULFONIC ACID-MODIFIED POLYISOCYANATE AND PREPARATION METHOD THEREFOR | TST, SULT1A1, SULT2A1 | ALDH1A1 1641/4885POLB 3322/4885MEN1 3118/4885 |
| US-20050059812-A1 | Process for insertion of acrylonitrile into a metal-carbon bond | NCLN, C9, P4HB | ALDH1A1 807/4885POLB 1460/4885MEN1 613/4885 |
| US-12559453-B2 | Sulfonic acid-modified polyisocyanate and preparation method therefor | TMT1A, SRMS, FTO | ALDH1A1 744/4885POLB 2438/4885MEN1 3395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.