Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP7 | P55210 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.49 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TTR | P02766 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7173911 | 0.86 | ELANE (0.75) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL16226853 | 0.85 | ELANE (0.74) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL23486216 | 0.84 | ELANE (0.72) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL14003223 | 0.82 | TTR (0.71) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL23486128 | 0.82 | ALDH1A1 (0.71) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL26187355 | 0.82 | ELANE (0.69) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL16226680 | 0.79 | ELANE (0.66) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL16226101 | 0.78 | ELANE (0.68) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL9878243 | 0.74 | ALDH1A1 (0.83) | ELANEALDH1A1MAPTKDM4EHPGD | |
| SCHEMBL3723343 | 0.74 | ELANE (0.58) | ELANEALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021110177-A1 | RHEIN DERIVATIVE AND ANTIVIRAL USE THEREOF | 中检科医药科技(北京)集团有限公司 | 2021-06-10 | — | — | WO | disclosed |
| WO-2009106909-A1 | PROCESS FOR THE PURIFICATION OF DIACEREIN | LABORATOIRE MEDIDOM S.A. (CH) | 2009-09-03 | — | — | WO | disclosed |
| WO-1996030034-A1 | PRODUCTION OF RHEIN AND RHEIN DERIVATIVES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-10-03 | — | — | WO | disclosed |