Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.83 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.83 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.83 |
| ▸ | ELANE | P08246 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | ACLY | P53396 | 2/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16226679 | 0.91 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL16226368 | 0.89 | ELANE (0.83) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL16227337 | 0.89 | ELANE (0.83) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL16226349 | 0.81 | ELANE (0.60) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL16226869 | 0.81 | ALDH1A1 (0.80) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL27921217 | 0.81 | ALDH1A1 (0.74) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL9878296 | 0.80 | ELANE (0.60) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL27882221 | 0.80 | ALDH1A1 (0.77) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL6905135 | 0.79 | ALDH1A1 (0.77) | ALDH1A1CYP1A2CYP3A4ELANEMAPT | |
| SCHEMBL16227270 | 0.79 | ALDH1A1 (0.70) | ALDH1A1CYP1A2CYP3A4ELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115850257-A | Synthetic method of emodin amide derivatives containing coumarin thiazole and application of emodin amide derivatives in resisting marine vibrio | 江苏海洋大学 | 2023-03-28 | — | — | CN | claimed |
| CN-112480031-B | Emodin amide derivatives containing 1,3, 4-thiadiazole, and synthesis method and application thereof | 江苏海洋大学 | 2022-05-20 | — | — | CN | claimed |
| CN-112480031-A | Emodin amide derivatives containing 1,3, 4-thiadiazole, and synthesis method and application thereof | 江苏海洋大学 | 2021-03-12 | — | — | CN | claimed |
| CN-102241598-B | Monohydroxy emodin dioctyl quaternary ammonium salt with anticancer activity | UNIV FUZHOU | 2014-07-09 | — | — | CN | claimed |
| CN-103819350-A | Chemical modification method capable of improving producing ability of reactive oxygen species (ROS) of rheum emodin | UNIV FUZHOU | 2014-05-28 | — | — | CN | claimed |
| CN-101941914-B | Hydroxyl whole-protection didecyl quaternary ammonium with anti-tumor activity and preparation method thereof | UNIV FUZHOU | 2013-08-07 | — | — | CN | claimed |
| CN-101967105-B | Beta-hydroxy protected didecyl quaternary ammonium salt with anticancer activity and preparation method thereof | UNIV FUZHOU | 2013-04-17 | — | — | CN | claimed |
| CN-102363044-B | Application of three anthraquinone substances of targeted mitochondria as nasopharyngeal darcinoma radiosensitizers | HOU HUAXIN | 2013-03-20 | — | — | CN | claimed |
| CN-102649765-A | Emodin di-n-octyl quaternary ammonium salt with anti-leukemia activity and preparation method thereof | FUJIAN MEDICAL UNIVERSITY UNION HOSPITAL | 2012-08-29 | — | — | CN | claimed |
| CN-102614158-A | Emodin derivative with antitumor activity and preparation method thereof | UNIV FUZHOU | 2012-08-01 | — | — | CN | claimed |
| CN-102363044-A | Application of three anthraquinone substances of targeted mitochondria as nasopharyngeal darcinoma radiosensitizers | HUAXIN HOU | 2012-02-29 | — | — | CN | claimed |
| CN-102249941-A | Monohydroxy di(n-decyl) emodin quaternary ammonium salt with anticancer activity | UNIV FUZHOU | 2011-11-23 | — | — | CN | claimed |
| CN-102241598-A | Monohydroxy emodin dioctyl quaternary ammonium salt with anticancer activity | UNIV FUZHOU | 2011-11-16 | — | — | CN | claimed |
| CN-102173997-A | Liver cancer, gastric cancer and cervical cancer-resistant archen derivative and preparation method thereof | UNIV FUZHOU | 2011-09-07 | — | — | CN | claimed |
| CN-101967105-A | Beta-hydroxy protected didecyl quaternary ammonium salt with anticancer activity and preparation method thereof | UNIV FUZHOU | 2011-02-09 | — | — | CN | claimed |
| CN-101941914-A | Hydroxyl whole-protection didecyl quaternary ammonium with anti-tumor activity and preparation method thereof | UNIV FUZHOU | 2011-01-12 | — | — | CN | claimed |
| CN-115850257-A | Synthetic method of emodin amide derivatives containing coumarin thiazole and application of emodin amide derivatives in resisting marine vibrio | 江苏海洋大学 | 2023-03-28 | — | — | CN | disclosed |
| CN-112480031-B | Emodin amide derivatives containing 1,3, 4-thiadiazole, and synthesis method and application thereof | 江苏海洋大学 | 2022-05-20 | — | — | CN | disclosed |
| US-5053431-A | Antitumor-anticarcinogenic agents | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1991-10-01 | — | — | US | disclosed |
| WO-1990008759-A1 | DERIVATIVES OF CHRYSOPHANOL | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 1990-08-09 | — | — | WO | disclosed |