Sugi Predict

Sugi Predict / Compounds / SCHEMBL310852

SCHEMBL310852

SCHEMBL310852

CC(C)(C)OC(=O)C1CCN(C(=O)O)CC1

nearest known ligand 0.60

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ HRH3 Q9Y5N1 1/20 0.60
▸ HPGD P15428 1/20 0.49
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ KMT2A Q03164 2/20 0.47
▸ ALDH1A1 P00352 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ TSHR P16473 1/20 0.47
▸ RECQL P46063 1/20 0.46
▸ HSD17B10 Q99714 1/20 0.46
▸ PTPN2 P17706 1/20 0.42
▸ PTPN1 P18031 1/20 0.42
▸ PTPN6 P29350 1/20 0.42
▸ LMNA P02545 1/20 0.42
▸ MAPT P10636 2/20 0.40
▸ GPR119 Q8TDV5 1/20 0.40
▸ EPHX1 P07099 1/20 0.40
▸ STS P08842 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4499465 0.89 HRH3 (0.54) HRH3HPGDSMN1; SMN2KMT2AALDH1A1
SCHEMBL750380 0.89 HRH3 (0.54) HRH3HPGDSMN1; SMN2KMT2AALDH1A1
SCHEMBL4493181 0.89 HRH3 (0.54) HRH3HPGDSMN1; SMN2KMT2AALDH1A1
SCHEMBL28055168 0.87 HRH3 (0.77) HRH3HPGDSMN1; SMN2KMT2AALDH1A1
Toluene SCHEMBL16765771 0.87 HRH3 (0.49) HRH3SMN1; SMN2KMT2AALDH1A1MEN1
SCHEMBL1764566 0.85 HRH3 (0.60) HRH3HPGDSMN1; SMN2KMT2AALDH1A1
SCHEMBL11904378 0.85 HPGD (0.66) HRH3HPGDSMN1; SMN2KMT2ARECQL
SCHEMBL25217807 0.84 HRH3 (0.59) HRH3HPGDSMN1; SMN2KMT2AALDH1A1
SCHEMBL30734430 0.84 HRH3 (0.59) HRH3HPGDSMN1; SMN2KMT2AALDH1A1
SCHEMBL4055980 0.81 HRH3 (0.55) HRH3HPGDSMN1; SMN2KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 442 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12178809-B2 Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-12-31 — — US disclosed
CN-112955215-B Pyridylsulfonamide derivatives, pharmaceutical compositions and uses thereof 勃林格殷格翰国际有限公司 2024-05-17 — — CN disclosed
WO-2024044744-A2 PEROXIREDOXIN 3 INHIBITORS AND METHODS OF USE FOR TREATING CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2024-02-29 — — WO disclosed
EP-3873600-B9 PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF BOEHRINGER INGELHEIM INT (DE) 2024-02-14 — — EP disclosed
EP-3873600-B1 PYRIDINYL SULFONAMIDE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF BOEHRINGER INGELHEIM INT (DE) 2023-09-20 — — EP disclosed
US-20230271963-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE VERTEX PHARMACEUTICALS (EUROPE) LIMITED (GB) 2023-08-31 — — US disclosed
EP-4190786-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE Vertex Pharmaceuticals Incorporated (US) 2023-06-07 — — EP disclosed
WO-2023049790-A2 MDM2 DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. (US) 2023-03-30 — — WO disclosed
EP-3808749-B1 PYRAZOLO[1,5-A]PYRIMIDINES USEFUL AS INHIBITORS OF ATR KINASE FOR THE TREATMENT OF CANCER DISEASES VERTEX PHARMA (US) 2023-03-08 — — EP disclosed
US-11370798-B2 Compounds useful as inhibitors of ATR kinase VERTEX PHARMACEUTICALS INCORPORATED (US) 2022-06-28 — — US disclosed
WO-2000039087-A2 SUBSTITUTED (AMINOIMINOMETHYL OR AMINOMETHYL)BENZOHETEROARYL COMPOUNDS AS FACTOR XA INHIBITORS AVENTIS PHARMACEUTICALS PRODUCTS INC. (US) 2000-07-06 — — WO disclosed
WO-2000014097-A2 NOVEL PYRANOSES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 2000-03-16 — — WO disclosed
US-5936089-A PIPERIDINE DERIVATIVES; BONE DISORDERS; OBESITY; AGING; CACHEXIA ASSOCIATED WITH AIDS AND CANCER PFIZER INC (US) 1999-08-10 — — US disclosed
CN-1214690-A Specific immunophilin ligands as antiasthmatics and immunosuppressants ASTA MEDICA AG (DE) 1999-04-21 — — CN disclosed
EP-0896580-A1 SPECIFIC IMMUNOPHILIN LIGANDS AS ANTIASTHMATICS AND IMMUNOSUPPRESSANTS ASTA Medica Aktiengesellschaft (DE) 1999-02-17 — — EP disclosed
EP-0828754-A1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER INC. (US) 1998-03-18 — — EP disclosed
WO-1997041148-A1 SPECIFIC IMMUNOPHILIN LIGANDS AS ANTIASTHMATICS AND IMMUNOSUPPRESSANTS ASTA MEDICA AKTIENGESELLSCHAFT (DE) 1997-11-06 — — WO disclosed
WO-1996038471-A1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER INC. (US) 1996-12-05 — — WO disclosed
CN-1136038-A Indoloylguanidine derivatives SUMITOMO PHARMACEUTICS K K (JP) 1996-11-20 — — CN disclosed
WO-1996035713-A1 DIPEPTIDES WHICH PROMOTE RELEASE OF GROWTH HORMONE PFIZER, INC. (US) 1996-11-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12178809-B2 Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof ARSA, SULT1A1, SULT2A1 HRH3 419/4885HPGD 598/4885SMN1; SMN2 1024/4885
US-20230271963-A1 COMPOUNDS USEFUL AS INHIBITORS OF ATR KINASE ATR, MAP3K20, TBK1 HRH3 3767/4885HPGD 3952/4885SMN1; SMN2 1281/4885
US-11370798-B2 Compounds useful as inhibitors of ATR kinase ATR, MAP3K20, TBK1 HRH3 3767/4885HPGD 3952/4885SMN1; SMN2 1281/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.