Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 2/20 | 0.67 |
| ▸ | MMP3 | P08254 | 1/20 | 0.67 |
| ▸ | CTSD | P07339 | 4/20 | 0.63 |
| ▸ | ADAMTS5 | Q9UNA0 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 4/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | MYC | P01106 | 1/20 | 0.54 |
| ▸ | MAX | P61244 | 1/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.54 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4056133 | 1.00 | MMP13 (0.67) | MMP13MMP3CTSDADAMTS5PTGS2 | |
| SCHEMBL7958249 | 0.83 | MMP13 (0.70) | MMP13MMP3CTSDADAMTS5PTGS2 | |
| SCHEMBL7958251 | 0.83 | MMP13 (0.70) | MMP13MMP3CTSDADAMTS5PTGS2 | |
| SCHEMBL7958571 | 0.83 | MMP13 (0.77) | MMP13MMP3CTSDADAMTS5PTGS2 | |
| SCHEMBL7958566 | 0.83 | MMP13 (0.77) | MMP13MMP3CTSDADAMTS5PTGS2 | |
| SCHEMBL11112353 | 0.81 | CSNK2A2 (0.64) | NPC1RAB9AMYCMAXCSNK2A2 | |
| SCHEMBL11112358 | 0.81 | CSNK2A2 (0.64) | NPC1RAB9AMYCMAXCSNK2A2 | |
| SCHEMBL4056380 | 0.81 | HPGD (0.82) | MMP13MMP3CTSDADAMTS5PTGS2 | |
| SCHEMBL1250159 | 0.81 | PTPN1 (0.82) | MMP13MMP3CTSDADAMTS5PTGS2 | |
| SCHEMBL1250155 | 0.81 | PTPN1 (0.82) | MMP13MMP3CTSDADAMTS5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |