Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | ACP1 | P24666 | 15/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060210 | 0.79 | HRH3 (0.45) | HRH3ACP1FFAR4TLR9TLR8 | |
| SCHEMBL1376616 | 0.78 | KCNH2 (0.56) | HRH3 | |
| SCHEMBL1374311 | 0.77 | HRH3 (0.77) | HRH3 | |
| SCHEMBL4055633 | 0.73 | PDE3B (0.43) | HRH3ACP1FFAR4TLR9TLR8 | |
| SCHEMBL27754056 | 0.71 | HRH3 (0.42) | HRH3 | |
| SCHEMBL4054814 | 0.71 | HRH3 (0.58) | HRH3 | |
| SCHEMBL4066308 | 0.69 | HRH3 (0.60) | HRH3ACP1 | |
| SCHEMBL4060149 | 0.69 | HRH3 (0.59) | HRH3ACP1 | |
| SCHEMBL4056596 | 0.68 | PDE4A (0.56) | HRH3ACP1 | |
| SCHEMBL19283162 | 0.67 | ACP1 (0.67) | ACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | disclosed |