SCHEMBL4056403

SCHEMBL4056403

Cc1ccc(C(c2cc(C)c(O)c(C)c2C)c2cc(C)c(O)c(C)c2C)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.39
KMT2A Q03164 5/20 0.39
GAA P10253 5/20 0.39
PTGS1 P23219 4/20 0.39
PTGS2 P35354 3/20 0.39
ALOX5 P09917 2/20 0.39
G6PD P11413 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TRPA1 O75762 2/20 0.33
LMNA P02545 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
TP53 P04637 1/20 0.33
CACNA1C Q13936 1/20 0.33
CHRM1 P11229 1/20 0.33
SLC6A2 P23975 1/20 0.33
ADRA1A P35348 1/20 0.33
HTR2B P41595 1/20 0.33
ACHE P22303 1/20 0.33
CHRNA7 P36544 1/20 0.32
CA1 P00915 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1417468 0.89 ESR1 (0.39) KMT2AGAAPTGS1PTGS2TRPA1
SCHEMBL14478047 0.89 CA1 (0.37) MEN1KMT2AGAAPTGS1PTGS2
SCHEMBL12922961 0.89 CA1 (0.37) MEN1KMT2AGAAPTGS1PTGS2
SCHEMBL30218223 0.89 ESR1 (0.39) KMT2AGAAPTGS1PTGS2TRPA1
SCHEMBL2992304 0.87 PTGS1 (0.49) GAAPTGS1PTGS2TRPA1LMNA
SCHEMBL30262493 0.87 PTGS1 (0.49) GAAPTGS1PTGS2TRPA1LMNA
SCHEMBL1176905 0.85 GAA (0.40) MEN1KMT2AGAAPTGS1PTGS2
SCHEMBL30485783 0.85 GAA (0.40) MEN1KMT2AGAAPTGS1PTGS2
SCHEMBL12004501 0.84 SENP1 (0.40) MEN1KMT2AGAAPTGS1PTGS2
SCHEMBL14666792 0.84 KDM4E (0.39) MEN1KMT2APTGS1PTGS2G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM MEN1 754/4885KMT2A 1062/4885GAA 3627/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.