Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | CASP7 | P55210 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935953 | 0.91 | CYP2C9 (0.38) | CYP2C9RENPOLBKMT2ACASP3 | |
| SCHEMBL3930886 | 0.91 | CYP2C9 (0.36) | CYP2C9RENPOLBKMT2ACASP3 | |
| SCHEMBL3935727 | 0.90 | CASP3 (0.39) | CYP2C9RENPOLBKMT2ACASP3 | |
| SCHEMBL3934977 | 0.90 | CYP2C9 (0.37) | CYP2C9RENPOLBKMT2ACASP3 | |
| SCHEMBL3929991 | 0.90 | CYP2C9 (0.35) | CYP2C9RENPOLBKMT2ACASP3 | |
| SCHEMBL3935732 | 0.90 | CASP3 (0.39) | CYP2C9RENPOLBKMT2ACASP3 | |
| SCHEMBL3930636 | 0.90 | CYP2C9 (0.35) | CYP2C9RENPOLBKMT2ACASP3 | |
| SCHEMBL3929981 | 0.89 | POLB (0.39) | CYP2C9RENPOLBKMT2ACASP3 | |
| SCHEMBL3938539 | 0.89 | RORC (0.36) | CYP2C9RENPOLBKMT2AMAPT | |
| SCHEMBL3938542 | 0.89 | RORC (0.36) | CYP2C9RENPOLBKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106599-A2 | SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS | NOVARTIS AG (CH) | 2009-09-03 | — | — | WO | disclosed |