SCHEMBL4056460

SCHEMBL4056460

CC(=O)c1ccc(CCOS(=O)(=O)c2ccc(C)cc2)s1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.44
ALDH1A1 P00352 6/20 0.44
RECQL P46063 2/20 0.44
LMNA P02545 2/20 0.44
PRNP P04156 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
STAT3 P40763 2/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
PSMD10 O75832 1/20 0.38
DHODH Q02127 1/20 0.37
PKM P14618 2/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
SIRT5 Q9NXA8 1/20 0.35
GSK3B P49841 1/20 0.35
MAPT P10636 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10731065 0.80 HPGD (0.41) HPGDALDH1A1RECQLLMNAPRNP
SCHEMBL10731053 0.80 HPGD (0.41) HPGDALDH1A1RECQLLMNAPRNP
SCHEMBL9685098 0.77 DHODH (0.38) HPGDALDH1A1RECQLLMNAPRNP
SCHEMBL10726039 0.77 DHODH (0.38) HPGDALDH1A1RECQLLMNAPRNP
SCHEMBL959744 0.75 PSMD10 (0.43) ALDH1A1RECQLSTAT3CA12CA1
SCHEMBL9257428 0.74 MAOB (0.49) HPGDALDH1A1LMNASTAT3CA1
SCHEMBL241884 0.73 CA1 (0.52) HPGDALDH1A1LMNASTAT3CA12
SCHEMBL1418052 0.72 MEN1 (0.46) ALDH1A1LMNACA12CA1CA9
SCHEMBL17763488 0.72 STAT3 (0.47) ALDH1A1LMNASTAT3CA12CA1
SCHEMBL4060893 0.72 ALDH1A1 (0.54) HPGDALDH1A1RECQLLMNAPRNP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009115644-A1 LANTHANIDE(III) CHELATES COMPRISING BETA-DIKETONES AND CONJUGATES DERIVED THEREOF WALLAC OY (FI) 2009-09-24 WO disclosed
WO-2009115644-A1 LANTHANIDE(III) CHELATES COMPRISING BETA-DIKETONES AND CONJUGATES DERIVED THEREOF WALLAC OY (FI) 2009-09-24 WO disclosed