SCHEMBL4060893

SCHEMBL4060893

CC(=O)OCCc1ccc(C(C)=O)s1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
LMNA P02545 3/20 0.54
PRNP P04156 1/20 0.54
RECQL P46063 1/20 0.54
RXFP1 Q9HBX9 1/20 0.54
HPGD P15428 1/20 0.54
GSK3B P49841 1/20 0.43
TSHR P16473 2/20 0.41
CA2 P00918 2/20 0.38
POLB P06746 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
CHRM5 P08912 2/20 0.37
CHRM1 P11229 2/20 0.37
CHRM3 P20309 2/20 0.37
PGR P06401 1/20 0.37
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
HTR1A P08908 1/20 0.37
CHRNB2 P17787 1/20 0.37
TBXA2R P21731 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29068719 0.87 ALDH1A1 (0.43) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL8652324 0.81 SMN1; SMN2 (0.41) ALDH1A1LMNATSHRCA2CHRM5
SCHEMBL12780984 0.81 ALDH1A1 (0.42) ALDH1A1LMNAHPGDTSHRCA2
SCHEMBL3057494 0.79 CA2 (0.41) ALDH1A1HPGDTSHRCA2CHRM5
SCHEMBL27748238 0.79 L3MBTL1 (0.44) ALDH1A1RXFP1HPGDGSK3BTSHR
SCHEMBL4058053 0.78 ALDH1A1 (0.60) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL3199622 0.78 ALDH1A1 (0.60) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL29068721 0.78 CA2 (0.37) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL27942739 0.78 CA2 (0.37) ALDH1A1LMNAPRNPRECQLRXFP1
SCHEMBL15898106 0.77 ALDH1A1 (0.38) ALDH1A1LMNAPRNPRECQLRXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009115644-A1 LANTHANIDE(III) CHELATES COMPRISING BETA-DIKETONES AND CONJUGATES DERIVED THEREOF WALLAC OY (FI) 2009-09-24 WO disclosed
WO-2009115644-A1 LANTHANIDE(III) CHELATES COMPRISING BETA-DIKETONES AND CONJUGATES DERIVED THEREOF WALLAC OY (FI) 2009-09-24 WO disclosed