Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2545818 | 0.72 | TSHR (0.45) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL473138 | 0.72 | TSHR (0.45) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL4629251 | 0.72 | ALDH1A1 (0.45) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL4629249 | 0.72 | ALDH1A1 (0.45) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL473141 | 0.72 | TSHR (0.45) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL4059127 | 0.71 | TET2 (0.32) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL4059119 | 0.71 | TET2 (0.32) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL4049311 | 0.69 | — | — | |
| SCHEMBL4226440 | 0.68 | TET2 (0.31) | — | |
| SCHEMBL4052219 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | claimed |
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |