Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4629251 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL4048367 | 0.77 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL1415787 | 0.76 | TSHR (0.43) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL4236652 | 0.74 | TET2 (0.33) | ALDH1A1TSHRTET2 | |
| SCHEMBL4056674 | 0.72 | HMGCR (0.30) | HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL4059127 | 0.72 | TET2 (0.32) | ALDH1A1HMGCRCHRM1TBXA2RADRA1A | |
| SCHEMBL2855633 | 0.65 | TSHR (0.36) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL2855707 | 0.65 | TSHR (0.36) | ALDH1A1TSHRHMGCRCHRM1TBXA2R | |
| SCHEMBL1058467 | 0.65 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL813445 | 0.65 | ALDH1A1 (0.35) | ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1720849-B1 | PYRANONE DERIVATIVES USEFUL FOR TREATING CANCER | CENTRE NAT RECH SCIENT (FR) | 2008-05-07 | — | — | EP | disclosed |
| EP-1720849-A1 | PYRANONE DERIVATIVES USEFUL FOR TREATING CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) Etablissement Public (FR) | 2006-11-15 | — | — | EP | disclosed |
| WO-2005073211-A1 | PYRANONE DERIVATIVES USEFUL FOR TREATING CANCER | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2005-08-11 | — | — | WO | disclosed |