Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PRKCG | P05129 | 1/20 | 0.34 |
| ▸ | PRKCB | P05771 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | PRKCA | P17252 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14177897 | 1.00 | HTR6 (0.46) | HTR6ALDH1A1MAPTCA12CA9 | |
| SCHEMBL4053320 | 1.00 | HTR6 (0.46) | HTR6ALDH1A1MAPTCA12CA9 | |
| SCHEMBL4049883 | 0.87 | HTR6 (0.46) | HTR6ALDH1A1MAPT | |
| SCHEMBL4049266 | 0.87 | HTR6 (0.46) | HTR6ALDH1A1MAPT | |
| SCHEMBL14177901 | 0.87 | HTR6 (0.46) | HTR6ALDH1A1MAPT | |
| SCHEMBL4058603 | 0.86 | HTR6 (0.53) | HTR6ALDH1A1MAPTHTR1AADRA1D | |
| SCHEMBL5785901 | 0.86 | HTR6 (0.53) | HTR6ALDH1A1MAPTHTR1AADRA1D | |
| SCHEMBL4047803 | 0.86 | HTR6 (0.53) | HTR6ALDH1A1MAPTHTR1AADRA1D | |
| SCHEMBL4050240 | 0.85 | HTR6 (0.43) | HTR6ALDH1A1ADRA1DADRA1AADRA1B | |
| SCHEMBL4057234 | 0.85 | HTR6 (0.43) | HTR6ALDH1A1ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1704154-B1 | NOVEL INDENO [2,1A]INDENES AND ISOINDOL [2,1-A]INDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2009-05-06 | — | — | EP | claimed |
| US-7388024-B2 | Indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-06-17 | — | — | US | claimed |
| US-20070054946-A1 | Novel indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-03-08 | — | — | US | claimed |
| EP-1704154-A1 | NOVEL INDENO [2,1A]INDENES AND ISOINDOL [2,1-A]INDOLES | Suven Life Sciences Limited (IN) | 2006-09-27 | — | — | EP | claimed |
| WO-2005066184-A1 | NOVEL INDENO[2,1A]INDENES AND ISOINDOL[2,1-A]INDOLES | SUVEN LIFE SCIENCES LIMITED (IN) | 2005-07-21 | — | — | WO | claimed |
| EP-1704154-B1 | NOVEL INDENO [2,1A]INDENES AND ISOINDOL [2,1-A]INDOLES | SUVEN LIFE SCIENCES LTD (IN) | 2009-05-06 | — | — | EP | disclosed |
| US-7388024-B2 | Indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2008-06-17 | — | — | US | disclosed |
| US-20070054946-A1 | Novel indeno[2,1A]indenes and isoindolo[2,1-A]indoles | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054946-A1 | Novel indeno[2,1A]indenes and isoindolo[2,1-A]indoles | IDO1, IDO2, OPRD1 | HTR6 166/4885ALDH1A1 547/4885MAPT 3548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.