SCHEMBL4057232

SCHEMBL4057232

CCCOc1ccc(-c2ccc(C(=O)OC(C)(C)C)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.53
PLK1 P53350 1/20 0.53
RARB P10826 4/20 0.52
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
ADRB2 P07550 1/20 0.52
ADRB1 P08588 1/20 0.52
ADRB3 P13945 1/20 0.52
MAPT P10636 5/20 0.50
SMN1; SMN2 Q16637 2/20 0.49
THRB P10828 1/20 0.48
TSHR P16473 2/20 0.46
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
TP53 P04637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19497928 0.89 CA12 (0.54) L3MBTL1RARBCA12CA1CA2
SCHEMBL4059293 0.88 ACACB (0.56) L3MBTL1PLK1ADRB2ADRB1ADRB3
SCHEMBL578611 0.86 MAPT (0.54) L3MBTL1RARBCA12CA1CA2
SCHEMBL6538605 0.83 ALDH1A1 (0.62) L3MBTL1PLK1RARBADRB2ADRB1
SCHEMBL14231641 0.83 MAPT (0.74) L3MBTL1PLK1RARBCA1CA2
SCHEMBL11887264 0.82 PARP10 (0.58) L3MBTL1PLK1MAPTLMNAKMT2A
SCHEMBL4065254 0.82 ELANE (0.55) L3MBTL1PLK1RARBMAPTSMN1; SMN2
SCHEMBL6350965 0.82 CA12 (0.71) CA12CA1CA2CA9CA14
SCHEMBL4843176 0.81 MAPT (0.53) L3MBTL1CA12CA1CA2CA9
SCHEMBL7409800 0.81 MAPT (0.53) L3MBTL1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
US-7534547-B2 Optically active compound and photosensitive resin composition OSAKA GAS COMPANY LIMITED (JP) 2009-05-19 US disclosed
EP-1375463-A1 OPTICALLY ACTIVE COMPOUND AND PHOTOSENSITIVE RESIN COMPOSITION Kansai Research Institute, Inc. (JP) 2004-01-02 EP disclosed
US-20030211421-A1 Optically active compound and photosensitive resin composition KRI, INC. (JP) 2003-11-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030211421-A1 Optically active compound and photosensitive resin composition ARCN1, RAD51, PAM L3MBTL1 2831/4885PLK1 4861/4885RARB 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.