SCHEMBL4057249

SCHEMBL4057249

CCCCCC(O)CCC(C)C

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.52
FFAR1 O14842 1/20 0.52
NFKB1 P19838 1/20 0.50
GPR84 Q9NQS5 7/20 0.48
CA1 P00915 2/20 0.46
SPHK1 Q9NYA1 1/20 0.46
FAAH O00519 2/20 0.44
OPRM1 P35372 1/20 0.44
FDPS P14324 2/20 0.43
ACE2 Q9BYF1 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16744186 1.00 FFAR4 (0.52) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL28277114 0.98 FFAR1 (0.55) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL8897084 0.98 FFAR1 (0.55) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL8388624 0.98 FFAR1 (0.55) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL17526843 0.92 FFAR4 (0.54) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL107867 0.92 FFAR4 (0.43) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL17526740 0.92 FFAR4 (0.54) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL16114411 0.90 FFAR1 (0.57) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL6759532 0.90 FFAR1 (0.57) FFAR4FFAR1NFKB1GPR84CA1
SCHEMBL11708323 0.90 FFAR4 (0.52) FFAR4FFAR1NFKB1GPR84CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250000088-A1 ANT CONTROL AGENT AND ANT CONTROL METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-01-02 US disclosed
EP-4424164-A1 ANT CONTROL AGENT AND ANT CONTROL METHOD SHIN-ETSU CHEMICAL CO., LTD. (JP) 2024-09-04 EP disclosed
CN-118139527-A Ant control agent and ant control method 信越化学工业株式会社 2024-06-04 CN disclosed
US-11795135-B2 Prostacyclin compounds, compositions and methods of use thereof INSMED INCORPORATED (US) 2023-10-24 US disclosed
US-11795135-B2 Prostacyclin compounds, compositions and methods of use thereof INSMED INCORPORATED (US) 2023-10-24 US disclosed
US-20230250051-A1 METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS INSMED INCORPORATED (US) 2023-08-10 US disclosed
US-20230250051-A1 METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS INSMED INCORPORATED (US) 2023-08-10 US disclosed
WO-2023074396-A1 ANT CONTROL AGENT AND ANT CONTROL METHOD 信越化学工業株式会社 2023-05-04 WO disclosed
US-11148997-B2 Methods of manufacturing treprostinil and treprostinil derivative prodrugs INSMED INCORPORATED (US) 2021-10-19 US disclosed
US-20210276940-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF BIOPHARMA CREDIT PLC (GB) 2021-09-09 US disclosed
US-20170320813-A1 METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS BIOPHARMA CREDIT PLC (GB) 2017-11-09 US disclosed
US-20170049739-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF INSMED INCORPORATED 2017-02-23 US disclosed
US-20170049739-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF INSMED INCORPORATED 2017-02-23 US disclosed
US-20160318844-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF INSMED INC (US) 2016-11-03 US disclosed
US-9469600-B2 Prostacyclin compounds, compositions and methods of use thereof INSMED INCORPORATED (US) 2016-10-18 US disclosed
US-20160256425-A1 Prostacyclin Compounds, Compositions and Methods of use Thereof BIOPHARMA CREDIT PLC (GB) 2016-09-08 US disclosed
US-9255064-B2 Prostacyclin compounds, compositions and methods of use thereof INSMED INCORPORATED (US) 2016-02-09 US disclosed
US-20150175529-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF BIOPHARMA CREDIT PLC (GB) 2015-06-25 US disclosed
US-20150148414-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF BIOPHARMA CREDIT PLC (GB) 2015-05-28 US disclosed
WO-2009123355-A2 COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2009-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230250051-A1 METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS PTGIS, THOP1, PTGIR FFAR4 1625/4885FFAR1 984/4885NFKB1 1719/4885
US-20210276940-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF PTGIS, PTGIR, PTGER1 FFAR4 1397/4885FFAR1 707/4885NFKB1 1422/4885
US-20170049739-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF PTGIS, PTGIR, PTGER1 FFAR4 1397/4885FFAR1 707/4885NFKB1 1422/4885
US-11148997-B2 Methods of manufacturing treprostinil and treprostinil derivative prodrugs PTGIS, PTGER1, PTGIR FFAR4 2099/4885FFAR1 984/4885NFKB1 1669/4885
US-20160318844-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF PTGIS, PTGER1, PTGER3 FFAR4 1278/4885FFAR1 435/4885NFKB1 2623/4885
US-20150148414-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF PTGIS, PTGIR, PTGER1 FFAR4 1397/4885FFAR1 707/4885NFKB1 1422/4885
US-20170320813-A1 METHODS OF MANUFACTURING TREPROSTINIL AND TREPROSTINIL DERIVATIVE PRODRUGS PTGIS, THOP1, PTGIR FFAR4 1691/4885FFAR1 1017/4885NFKB1 1646/4885
US-11795135-B2 Prostacyclin compounds, compositions and methods of use thereof PTGIS, PTGIR, PTGER1 FFAR4 1397/4885FFAR1 707/4885NFKB1 1422/4885
US-20160256425-A1 Prostacyclin Compounds, Compositions and Methods of use Thereof PTGIS, PTGIR, PTGER1 FFAR4 1397/4885FFAR1 707/4885NFKB1 1422/4885
US-20150175529-A1 PROSTACYCLIN COMPOUNDS, COMPOSITIONS AND METHODS OF USE THEREOF PTGIS, PTGIR, PTGER1 FFAR4 1397/4885FFAR1 707/4885NFKB1 1422/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.