Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA3 | P07451 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | CA6 | P23280 | 1/20 | 0.49 |
| ▸ | CA5A | P35218 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057267 | 1.00 | KMT2A (0.54) | KMT2ARIPK1LMNARAB9AMME | |
| SCHEMBL13946518 | 1.00 | KMT2A (0.54) | KMT2ARIPK1LMNARAB9AMME | |
| SCHEMBL15623829 | 0.89 | FNTA (0.45) | KMT2ALMNAALDH1A1MEN1OPRK1 | |
| SCHEMBL13690882 | 0.85 | EPHX2 (0.54) | KMT2AMEN1CA1CA2CA7 | |
| SCHEMBL13690868 | 0.84 | NPC1 (0.56) | KMT2ARAB9AMMP8ALDH1A1MEN1 | |
| SCHEMBL13690884 | 0.84 | LMNA (0.56) | LMNARAB9AALDH1A1CYP3A4MAPT | |
| SCHEMBL15680216 | 0.83 | CYP1A2 (0.46) | OPRK1CYP1A2CYP2D6CYP2C9TSHR | |
| SCHEMBL13690886 | 0.82 | PKM (0.64) | KMT2ALMNAALDH1A1CYP3A4SMN1; SMN2 | |
| SCHEMBL13690869 | 0.81 | KMT2A (0.66) | KMT2ARAB9AMMP8ALDH1A1CYP2D6 | |
| SCHEMBL4743536 | 0.81 | KMT2A (0.59) | KMT2AMMEMMP8ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | disclosed |