Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4070379 | 0.94 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL14289235 | 0.91 | EDNRB (0.86) | EDNRAEDNRB | |
| SCHEMBL14289225 | 0.90 | EDNRB (0.85) | EDNRAEDNRB | |
| SCHEMBL795169 | 0.90 | EDNRA (0.88) | EDNRAEDNRB | |
| SCHEMBL6654039 | 0.87 | EDNRA (0.83) | EDNRAEDNRB | |
| SCHEMBL14289233 | 0.84 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL5493621 | 0.82 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL14289234 | 0.82 | EDNRB (0.84) | EDNRAEDNRB | |
| SCHEMBL14289224 | 0.81 | EDNRB (0.82) | EDNRAEDNRB | |
| SCHEMBL4069236 | 0.79 | EDNRA (0.78) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322624-B1 | ARYLALKANE-SULFONAMIDES HAVING ENDOTHELIN-ANTAGONIST ACTIVITY | ACTELION PHARMACEUTICALS LTD (CH) | 2009-10-21 | — | — | EP | claimed |