Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13639825 | 0.90 | KMT2A (0.47) | SRD5A1KMT2AHRH3SRD5A2POLB | |
| SCHEMBL1375233 | 0.87 | GPR119 (0.54) | SRD5A1KMT2ALMNAMAPT | |
| SCHEMBL4682743 | 0.79 | SRD5A1 (0.67) | SRD5A1KMT2AHRH3SRD5A2LMNA | |
| SCHEMBL22694560 | 0.77 | KMT2A (0.51) | SRD5A1KMT2AHRH3SRD5A2LMNA | |
| SCHEMBL27900126 | 0.76 | PARP10 (0.67) | SRD5A1KMT2ASRD5A2POLBLMNA | |
| SCHEMBL3341121 | 0.76 | POLB (0.54) | SRD5A1KMT2ASRD5A2POLBLMNA | |
| SCHEMBL2636897 | 0.76 | EPHX2 (0.60) | SRD5A1KMT2ASRD5A2MEN1 | |
| SCHEMBL5931431 | 0.75 | EPHX2 (0.62) | SRD5A1KMT2AHRH3SRD5A2LMNA | |
| SCHEMBL18101745 | 0.74 | PARP10 (0.47) | KMT2AHRH3POLBMEN1NAMPT | |
| SCHEMBL18101744 | 0.74 | PARP10 (0.47) | KMT2AHRH3LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2069312-A2 | PYRIDIZINONE DERIVATIVES | Cephalon, Inc. (US) | 2009-06-17 | — | — | EP | disclosed |
| WO-2008013838-A2 | PYRIDIZINONE DERIVATIVES | CEPHALON, INC. (US) | 2008-01-31 | — | — | WO | disclosed |