Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4060299 | 1.00 | PPARA (0.40) | PPARAPPARGALDH1A1GAAL3MBTL1 | |
| SCHEMBL4050986 | 0.83 | CYP1A2 (0.39) | PPARAPPARGALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4055070 | 0.82 | NPC1 (0.40) | PPARAPPARGALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4052380 | 0.82 | NPC1 (0.40) | PPARAPPARGALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4049541 | 0.82 | NPC1 (0.40) | PPARAPPARGALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4056607 | 0.82 | NPC1 (0.40) | PPARAPPARGALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL4062324 | 0.74 | NPSR1 (0.45) | PPARAPPARGALDH1A1GAAKMT2A | |
| SCHEMBL4050550 | 0.73 | LMNA (0.47) | ALDH1A1KMT2ALMNATSHR | |
| SCHEMBL4058620 | 0.73 | LMNA (0.47) | ALDH1A1KMT2ALMNATSHR | |
| SCHEMBL4052162 | 0.73 | LMNA (0.47) | ALDH1A1KMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009110655-A1 | NOVEL BETA SUBSTITUTED MORITA-BAYLIS-HILLMAN DERIVATIVES | SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE COLLABORATION (KR) | 2009-09-11 | — | — | WO | disclosed |