Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 13/20 | 0.57 |
| ▸ | CNR2 | P34972 | 9/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4059464 | 0.91 | CNR1 (0.49) | CNR1CNR2 | |
| SCHEMBL13690985 | 0.91 | CNR1 (0.51) | CNR1CNR2ADORA2AADORA1SSTR4 | |
| SCHEMBL4053936 | 0.91 | CNR1 (0.51) | CNR1CNR2ADORA2AADORA1SSTR4 | |
| SCHEMBL4052559 | 0.90 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL13690740 | 0.90 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL13691063 | 0.90 | CNR1 (0.49) | CNR1CNR2ADORA2AADORA1SSTR4 | |
| SCHEMBL4058510 | 0.89 | CNR1 (0.48) | CNR1CNR2ADORA2AADORA1SSTR4 | |
| SCHEMBL13690712 | 0.88 | CNR1 (0.49) | CNR1CNR2SSTR4 | |
| SCHEMBL13691004 | 0.88 | CNR1 (0.47) | CNR1CNR2ADORA2AADORA1SSTR4 | |
| SCHEMBL4049851 | 0.88 | CNR1 (0.47) | CNR1CNR2ADORA2AADORA1SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |