Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.49 |
| ▸ | CNR2 | P34972 | 9/20 | 0.49 |
| ▸ | HTR4 | Q13639 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4057752 | 0.91 | CNR1 (0.57) | CNR1CNR2 | |
| SCHEMBL4051582 | 0.91 | CNR1 (0.42) | CNR1CNR2HTR4CYP3A4HTR3A | |
| SCHEMBL13690954 | 0.90 | CNR1 (0.41) | CNR1CNR2HTR4CYP3A4HTR3A | |
| SCHEMBL13690587 | 0.89 | HTR4 (0.42) | CNR1CNR2HTR4CYP3A4HTR3A | |
| SCHEMBL4059133 | 0.89 | HTR4 (0.42) | CNR1CNR2HTR4CYP3A4HTR3A | |
| SCHEMBL13691151 | 0.89 | CNR1 (0.42) | CNR1CNR2HTR4CYP3A4HTR3A | |
| SCHEMBL13690740 | 0.89 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL4052559 | 0.89 | CNR1 (0.48) | CNR1CNR2 | |
| SCHEMBL13691009 | 0.88 | CNR1 (0.41) | CNR1CNR2HTR4CYP3A4HTR3A | |
| SCHEMBL4048417 | 0.88 | CNR1 (0.41) | CNR1CNR2HTR4CYP3A4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106980-A2 | INDAZOLE DERIVATIVES | PFIZER INC. (US) | 2009-09-03 | — | — | WO | claimed |