Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.49 |
| ▸ | MYC | P01106 | 1/20 | 0.47 |
| ▸ | MAX | P61244 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4051802 | 1.00 | MEN1 (0.49) | MEN1KMT2AADAMTS5CISD1MYC | |
| SCHEMBL4053039 | 0.85 | MYC (0.56) | MEN1KMT2AMYCMAXPOLB | |
| SCHEMBL4053037 | 0.85 | MYC (0.56) | MEN1KMT2AMYCMAXPOLB | |
| SCHEMBL4056856 | 0.84 | ENPP2 (0.58) | MEN1KMT2AADAMTS5CISD1MYC | |
| SCHEMBL4057769 | 0.84 | MYC (0.57) | MEN1KMT2AMYCMAXPOLB | |
| SCHEMBL4057766 | 0.84 | MYC (0.57) | MEN1KMT2AMYCMAXPOLB | |
| SCHEMBL4056858 | 0.84 | ENPP2 (0.58) | MEN1KMT2AADAMTS5CISD1MYC | |
| SCHEMBL4057761 | 0.81 | ADAMTS5 (0.75) | MEN1KMT2AADAMTS5CISD1HPGD | |
| SCHEMBL4057759 | 0.81 | ADAMTS5 (0.75) | MEN1KMT2AADAMTS5CISD1HPGD | |
| SCHEMBL4054938 | 0.79 | KMT2A (0.40) | MEN1KMT2AADAMTS5CISD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009109999-A1 | NOVEL PROTEIN TYROSINE PHOSPHATASE - IB INHIBITORS | LUPIN LIMITED (IN) | 2009-09-11 | — | — | WO | disclosed |