Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.41 |
| ▸ | CNR1 | P21554 | 4/20 | 0.38 |
| ▸ | SLC34A1 | Q06495 | 4/20 | 0.38 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.34 |
| ▸ | IDH2 | P48735 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | XIAP | P98170 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.33 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.33 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464803 | 0.91 | CNR2 (0.42) | CNR2CNR1SLC34A1NTRK1DHODH | |
| SCHEMBL1464800 | 0.87 | CNR2 (0.52) | CNR2CNR1PHGDHKCNJ6KCNJ5 | |
| SCHEMBL1465718 | 0.81 | CNR2 (0.49) | CNR2CNR1NTRK1PHGDH | |
| SCHEMBL1464703 | 0.76 | CNR2 (0.57) | CNR2CNR1NTRK1 | |
| SCHEMBL1463758 | 0.76 | CNR2 (0.69) | CNR2CNR1 | |
| SCHEMBL1464781 | 0.74 | MMP1 (0.45) | CNR2NTRK1 | |
| SCHEMBL14319137 | 0.73 | SLC34A1 (0.40) | SLC34A1NTRK1DHODH | |
| SCHEMBL3964766 | 0.73 | CNR2 (0.47) | CNR2CNR1NTRK1PHGDH | |
| SCHEMBL1465811 | 0.72 | CNR2 (0.75) | CNR2CNR1PHGDH | |
| SCHEMBL1464950 | 0.71 | RORC (0.49) | CNR2CNR1DHODHXIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2081905-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-29 | — | — | EP | claimed |
| WO-2008014199-A2 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-01-31 | — | — | WO | claimed |