Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4048482 | 0.87 | GPR119 (0.56) | GPR119 | |
| SCHEMBL13690362 | 0.82 | GPR119 (0.41) | GPR119CYP2C9 | |
| SCHEMBL4561845 | 0.82 | GPR119 (0.50) | GPR119 | |
| SCHEMBL389322 | 0.81 | GPR119 (0.62) | GPR119CYP2C9KCNH2 | |
| SCHEMBL4057702 | 0.81 | GPR119 (0.48) | GPR119KCNH2 | |
| SCHEMBL386557 | 0.81 | GPR119 (0.64) | GPR119CYP2C9KCNH2 | |
| SCHEMBL3980850 | 0.80 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4057221 | 0.78 | GPR119 (0.53) | GPR119 | |
| SCHEMBL4048254 | 0.78 | GPR119 (0.46) | GPR119 | |
| SCHEMBL387662 | 0.78 | GPR119 (0.62) | GPR119CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |
| WO-2009106561-A1 | PYRAZINE COMPOUNDS FOR TREATING GPR119 RELATED DISORDERS | BIOVITRUM AB (PUBL) (SE) | 2009-09-03 | — | — | WO | disclosed |