Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3388119 | 0.83 | DRD2 (0.44) | MAPTPOLBKDM4EGAADRD2 | |
| SCHEMBL13460189 | 0.82 | MAPT (0.48) | MAPTRXFP1POLBKDM4EGAA | |
| SCHEMBL3388058 | 0.77 | MAPT (0.48) | MAPTRXFP1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL1997416 | 0.76 | MAPT (0.50) | MAPTRXFP1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL4591850 | 0.75 | MAPT (0.63) | MAPTRXFP1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL17848670 | 0.73 | MAPT (0.50) | MAPTRXFP1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL20224820 | 0.73 | MAPT (0.54) | MAPTRXFP1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL12530648 | 0.72 | KDM4E (0.51) | MAPTRXFP1POLBKDM4ESMN1; SMN2 | |
| SCHEMBL27739333 | 0.71 | MAPT (0.49) | MAPTRXFP1POLBKDM4EGAA | |
| SCHEMBL26817055 | 0.71 | MAPT (0.54) | MAPTRXFP1POLBKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009122180-A1 | PYRIMIDINE DERIVATIVES CAPABLE OF INHIBITING ONE OR MORE KINASES | MEDICAL RESEARCH COUNCIL (GB) | 2009-10-08 | — | — | WO | disclosed |