Iodide

Iodide

SCHEMBL4058733

C=CCn1c(C)c(C)[n+](CC=C)c1C.[I-]

nearest known ligand 0.34

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.34
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
TNNI3 P19429 1/20 0.31
TNNT2 P45379 1/20 0.31
TNNC1 P63316 1/20 0.31
KMT2A Q03164 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
GPR35 Q9HC97 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9282194 0.98 CYP3A4 (0.35) CYP3A4
SCHEMBL3313925 0.75
SCHEMBL3313929 0.75 CYP3A4 (0.38) CYP3A4MEN1USP2TNNI3TNNT2
SCHEMBL10602865 0.63 ALDH1A1 (0.51) MEN1KMT2A
SCHEMBL8640814 0.57 KMT2A (0.43) CYP3A4MEN1USP2TNNI3TNNT2
SCHEMBL20861812 0.57 CYP3A4 (0.46) CYP3A4MEN1KMT2A
SCHEMBL8027716 0.57 CYP3A4 (0.35) CYP3A4MEN1KMT2A
Iodide SCHEMBL9358702 0.56 CYP3A4 (0.31) CYP3A4
SCHEMBL5474378 0.56 CYP3A4 (0.34) CYP3A4
SCHEMBL30646141 0.56 CA1 (0.38) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0479463-B1 Process for the production of carboxylic acid anhydrides BP CHEM INT LTD (GB) 1995-12-13 EP claimed
EP-0479463-A2 Process for the production of carboxylic acid anhydrides BP Chemicals Limited (GB) 1992-04-08 EP claimed
JP-4257538-A None JP disclosed
US-20090177007-A1 PROCESS FOR PRODUCING CARBOXYLIC ACID ANHYDRIDES CHINA PETROCHEMICAL DEVELOPMENT CORPORATION 2009-07-09 US disclosed
US-7553991-B1 Process for producing carboxylic acid anhydrides CHINA PETROCHEMICAL DEVELOPMENT CORPORATION (TW) 2009-06-30 US disclosed
EP-0584964-B1 Process for the recovery of group VIII noble metals BP CHEM INT LTD (GB) 1998-08-26 EP disclosed
CN-1033698-C Process for production of carboxylic cid anhydrides BP CHEM INT LTD (GB) 1997-01-01 CN disclosed
EP-0535825-B1 Process for the purification of carboxylic acids and/or their anhydrides BP CHEM INT LTD (GB) 1996-05-08 EP disclosed
EP-0479463-B1 Process for the production of carboxylic acid anhydrides BP CHEM INT LTD (GB) 1995-12-13 EP disclosed
US-5364822-A Process for the recovery of group VIII noble metals BP CHEMICALS LIMITED (GB) 1994-11-15 US disclosed
US-5298586-A Reacting carbon monoxide with carboxylic acid, ester or alkyl ether in presence of rhodium catalyst and iodide promoter BP CHEMICALS LIMITED (GB) 1994-03-29 US disclosed
US-5298586-A Reacting carbon monoxide with carboxylic acid, ester or alkyl ether in presence of rhodium catalyst and iodide promoter BP CHEMICALS LIMITED (GB) 1994-03-29 US disclosed
EP-0584964-A1 Process for the recovery of group VIII noble metals BP Chemicals Limited (GB) 1994-03-02 EP disclosed
US-5227520-A Distillation, iodide promoter, rhodium catalyst BP CHEMICALS LIMITED (GB) 1993-07-13 US disclosed
EP-0535825-A2 Process for the purification of carboxylic acids and/or their anhydrides BP Chemicals Limited (GB) 1993-04-07 EP disclosed
JP-H04257538-A PRODUCTION OF CARBOXYLIC ANHYDRIDE BP CHEM INTERNATL LTD 1992-09-11 JP disclosed
EP-0479463-A2 Process for the production of carboxylic acid anhydrides BP Chemicals Limited (GB) 1992-04-08 EP disclosed
EP-0479463-A2 Process for the production of carboxylic acid anhydrides BP Chemicals Limited (GB) 1992-04-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090177007-A1 PROCESS FOR PRODUCING CARBOXYLIC ACID ANHYDRIDES CA9, CA4, CA6 CYP3A4 111/4885MEN1 4479/4885USP2 1074/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.