Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29840757 | 0.84 | NPC1 (0.45) | MDM2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL5542787 | 0.84 | MDM2 (0.36) | MDM2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL29947384 | 0.84 | IDO1 (0.44) | MDM2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL2122583 | 0.84 | NPC1 (0.45) | MDM2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL29840696 | 0.84 | IDO1 (0.46) | NPC1RAB9AKDM4EMAPTCYP1A2 | |
| SCHEMBL30538068 | 0.84 | IDO1 (0.44) | NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL1176651 | 0.84 | MDM2 (0.36) | MDM2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL700662 | 0.84 | ALDH1A1 (0.48) | MDM2NPC1RAB9AKDM4EMAPT | |
| SCHEMBL4714608 | 0.84 | CASP3 (0.44) | NPC1RAB9AKDM4EMAPTCYP1A2 | |
| SCHEMBL2123489 | 0.84 | IDO1 (0.46) | NPC1RAB9AKDM4EMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1801107-B1 | Process for the preparation of phenylenebisisoxazoles | EVONIK DEGUSSA GMBH (DE) | 2009-07-15 | — | — | EP | disclosed |
| EP-1801107-A1 | Process for the preparation of phenylenebisisoxazoles | Degussa GmbH (DE) | 2007-06-27 | — | — | EP | disclosed |