Dihydrospingosine

Dihydrospingosine

SCHEMBL40591

CCCCCCCCCCCCCCCC(O)C(N)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 4/20 1.00
SPHK1 Q9NYA1 4/20 1.00
LMNA P02545 4/20 1.00
MAPT P10636 4/20 1.00
GMNN O75496 3/20 1.00
POLB P06746 3/20 1.00
BLM P54132 3/20 1.00
CETP P11597 3/20 1.00
UBE2N P61088 3/20 1.00
THPO P40225 2/20 1.00
TP53 P04637 2/20 1.00
CYP1A2 P05177 2/20 1.00
MTOR P42345 1/20 1.00
KDM4E B2RXH2 1/20 1.00
CYP3A4 P08684 1/20 1.00
HTT P42858 1/20 1.00
CSNK1E P49674 1/20 0.54
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
GLA P06280 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1907293 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL18127645 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
Dihydrospingosine SCHEMBL7106054 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL8746720 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL1901499 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
Dihydrospingosine SCHEMBL3509781 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
Dihydrospingosine SCHEMBL13285654 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
Dihydrospingosine SCHEMBL1905632 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL21660227 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN
SCHEMBL21431064 1.00 CYP2D6 (1.00) CYP2D6SPHK1LMNAMAPTGMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2961 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3595621-B1 ANTIMICROBIAL COMPOSITION COMPRISING THYMOL OR TERPINEOL AND AN ANTIMICROBIAL LIPID UNILEVER GLOBAL IP LTD (GB) 2026-05-27 EP claimed
US-20260102500-A1 PKC INHIBITORS FOR THE TREATMENT OF SEPTIC CHOLESTASIS WITH POLYMETHINE DYE TARGETING SMARTDYELIVERY GMBH (DE) 2026-04-16 US claimed
EP-4685153-A1 BROAD-SPECTRUM VIRAL MEMBRANE FUSION INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF Henan Genuine Biotech Co., Ltd. (CN) 2026-01-28 EP claimed
US-20250360072-A1 OINTMENTS FOR TREATING DRY SKIN OCUSOFT INC (US) 2025-11-27 US claimed
EP-4624449-A1 VEGETABLE OIL CERAMIDES, SYNTHESIS METHOD THEREFOR, AND USE THEREOF Shenzhen Dikeman Biotechnology Co., Ltd. (CN) 2025-10-01 EP claimed
EP-4617282-A1 MEMBRANE FUSION INHIBITOR FOR INHIBITING AIDS VIRUS AND DRUG-RESISTANT STRAIN THEREOF, AND PHARMACEUTICAL USE THEREOF Institute Of Pathogen Biology, Chinese Academy Of Medical Sciences (CN) 2025-09-17 EP claimed
US-20250268913-A1 PKC INHIBITORS FOR THE TREATMENT OF SEPTIC CHOLESTASIS WITH CTM TARGETING SMARTDYELIVERY GMBH (DE) 2025-08-28 US claimed
US-12396937-B2 Ointments for treating dry skin OCUSOFT, INC. (US) 2025-08-26 US claimed
CN-119119165-B Centella asiatica derived ceramide and synthetic method and application thereof 深圳市迪克曼生物科技有限公司 2025-06-17 CN claimed
CN-120000585-A Novel drug-assisted precursor micelle preparation and production method thereof 酰莱(合肥)生命科学研发有限公司 2025-05-16 CN claimed
WO-1993020038-A1 SELECTIVE N-ACYLATION OF AMINO ALCOHOLS GIST-BROCADES N.V. (NL) 1993-10-14 WO claimed
US-H1168-H Antiinflammatory agent for improving tissue and body organ recovering from bacteria infection consisting of lipid analoges in carrier THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1993-04-06 US claimed
EP-0072286-B2 ORGANIC AMIDE COMPOUNDS DERIVED FROM NITROGENOUS LIPIDS FIDIA S.p.A. (IT) 1992-12-09 EP claimed
EP-0500437-A1 Ceramides, method for their preparation and their application in cosmetics and dermopharmacy L'OREAL (FR) 1992-08-26 EP claimed
EP-0207984-B1 ANTIVIRAL AGENTS SYMBICOM AB (SE) 1991-07-03 EP claimed
EP-0420722-A2 Lipid compounds, derivatives of sphingosines, process for their preparation and their use, especially in cosmetics and in dermopharmaceutics L'OREAL (FR) 1991-04-03 EP claimed
EP-0373038-A2 New lysosphingolipid derivatives FIDIA S.p.A. (IT) 1990-06-13 EP claimed
EP-0072286-B1 ORGANIC AMIDE COMPOUNDS DERIVED FROM NITROGENOUS LIPIDS FIDIA S.p.A. (IT) 1986-10-29 EP claimed
EP-0072286-A1 Organic amide compounds derived from nitrogenous lipids FIDIA S.p.A. (IT) 1983-02-16 EP claimed
US-4235792-A Immunological materials THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 1980-11-25 US claimed